Medicine Preview
Bachelor	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Course Introduction and Application Information

Course Code:

UNI347

Course Name:

The Relationship between Metabolic Paths and Health in the Organism

Semester:

Spring
Fall

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Yes

Type of course:

University Elective

Course Level:

Bachelor

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

E-Learning

Course Coordinator:

Prof. Dr. HİKMET KOÇAK

Course Lecturer(s):

Prof. Dr. Hikmet Koçak

Course Assistants:

Course Objective and Content

Course Objectives:

In this courses where the chemical reactions occurring in living organisms are studied; the metabolic events in which the biomolecules like proteins, carbohydrates and lipids take place and their interactions with each other will be explained to the students. It is also aimed to gain the competencies related to metabolism, to establish some relationships with biochemistry in the professional field and to gain the ability to evaluate them as a whole.

Course Content:

It is the functioning of the main metabolic pathways of the organism in a healthy state and raising awareness about pathological conditions in daily life.

Learning Outcomes

The students who have succeeded in this course;
1) Must be able to distinguish the structural differences of biochemical macromolecules.
2) Must be able to list the concept of nutritional energy sources and the body’s energy stores.
3) Must be able to explain the energy metabolism of carbohydrates, lipids, protein.
4) Must define postprandial status and explain hormonal changes in postprandial status.
5) Must be able to explain the digestion, absorption and outcome of food.
6) Must be able to explain the conversion pathways of glucose in the liver and its metabolism in other tissues.
7) Must be able to explain the outcome of lipoproteins and amino acids in postprandial status.
8) Must be able to define fasting and explain the metabolic changes in short-term fasting.
9) Must be able to explain the role of liver and adipose tissue in short term fasting.
10) Must be able to explain the occurring metabolic changes and roles of liver and adipose tissue in prolonged fasting.
11) Must be able to explain the basal metabolism (resting metabolic rate), physical activity, and control of body weight.
12) Must be able to explain the importance of carbohydrates, essential fatty acids, essential amino acids, vitamins and minerals which suply the basic nutritional requirements.

Course Flow Plan

Week	Subject	Related Preparation
1)	Basic Concepts and Explanation of The Syllabus	Lecture Notes-presentations notes
2)	Structural Overview of Basic Elements of Metabolic Pathways in the Organism	Lecture Notes-presentations notes
3)	Events Affecting the Energy Requirement of the Body	Lecture Notes-presentations notes
4)	Proteins- definition, properties, structure, types and Metabolism	Lecture Notes-presentations notes
5)	Lipid Metabolism	Lecture Notes-presentations notes
6)	The Carbohydrates and Metabolism	Lecture Notes-presentations notes
7)	Integration of Metabolism (fasting/starving-fed state, postprandial Status)	Lecture Notes-presentations notes
8)	Ramadan Feast (Holiday)
9)	Student Presentations
10)	Student Presentations
11)	Student Presentations
12)	Student Presentations
13)	Student Presentations
14)	Student Presentations

Sources

Course Notes / Textbooks:

Ders Notları-sunumlar
Lecture Notes-presentations notes

References:

1. Tıbbi Biyokimya, Gürdöl F., Nobel Tıp Kitabevleri, İstanbul, 2019
2. Harper'ın Biyokimyası, Nobel Tıp Kitabevleri, İstanbul, 2016
3. Lippincott Görsel Anlatımlı çalışma Kitapları Biyokimya, Harvey RA, Ferrier DR. (Çeviri editörü: Ulukaya E.): 5. baskı, Nobel Tıp Kitabevleri, 2014
4. Marks’ Tıbbi Biyokimyanın Esasları Klinik yaklaşım, Lieberman M, Peet A. (Çeviri editörleri: Amanvermez R, Avcı B.): 2nd edition, İstanbul Tıp Kitabevleri, 2017

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5	6	7	8	9	10	11	12
Program Outcomes
1) When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.
2) knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.
3) is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.
4) knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.
5) can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.
6) knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7) can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8) knows the clinical decision-making process, evidence-based medicine practices and current approaches.
9) knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10) knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11) is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12) knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.
13) can collect health data, analyze them, present them in summary, and prepare forensic reports.
14) knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.
15) knows employee health, environment and occupational safety issues and takes responsibility when necessary.
16) knows health policies and is able to evaluate their effects in the field of application.
17) keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.
18) applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.
2)	knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.
3)	is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.
4)	knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.
5)	can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.
6)	knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7)	can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8)	knows the clinical decision-making process, evidence-based medicine practices and current approaches.
9)	knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10)	knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11)	is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12)	knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.
13)	can collect health data, analyze them, present them in summary, and prepare forensic reports.
14)	knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.
15)	knows employee health, environment and occupational safety issues and takes responsibility when necessary.
16)	knows health policies and is able to evaluate their effects in the field of application.
17)	keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.
18)	applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Attendance	1	% 10
Homework Assignments	1	% 45
Presentation	1	% 45
total		% 100
PERCENTAGE OF SEMESTER WORK		% 100
PERCENTAGE OF FINAL WORK		%
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	2	0	14	16	60
Study Hours Out of Class	1	4	4	10	18
Presentations / Seminar	1	4	4	10	18
Homework Assignments	1	5	4	10	19
Total Workload					115