Medicine Preview
Bachelor	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Course Introduction and Application Information

Course Code:

TIP053

Course Name:

Bioinformatics

Semester:

Fall
Spring

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

Bachelor

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

E-Learning

Course Coordinator:

Dr. Öğr. Üy. ASLI KUTLU

Course Lecturer(s):

ASLI KUTLU

Course Assistants:

Course Objective and Content

Course Objectives:	To transform basic knowledge and equipment for medical education on bioinformatics applications and education. To create knowledge about education in general from the holistic and private private sectors. Based on basic gene and protein information, to equip you with the disease to progress.
Course Content:	Fundamentals of gene and protein expression -Procedural methods of gene and protein expression -The importance of pathway information in revealing disease mechanisms of action - Genome sequencing techniques and interpretation of the results -Bioinformatics-based approaches in personalized medicine applications -Structural bioinformatics applications

Learning Outcomes

The students who have succeeded in this course;
1) Cognitive and procedural applications of basic biochemistry knowledge
2) Gaining basic knowledge and application skills about bioinformatics applications
3) Revealing gene and protein expression patterns and gaining practice and meaning skills
4) Understanding the effects of genome sequencing applications on clinical approaches
5) Understanding the importance of operational methods in the development of clinical skills

Course Flow Plan

Week	Subject	Related Preparation
1)	Introduction to basic molecular biology & Alignment approaches
2)	DNA and protein alignments: multiple alignment, star alignment, and web tools
3)	Whole Exome Sequencing, Next-Generation Sequencing, and RNA seq approaches
4)	Genomics, Regulatory Genomics, and Epigenomics
5)	Protein Structure &Function, Proteomics, and Alternative Splicing
6)	Multi-omics integrative biology & Personalized medicine approach
7)	Midterm
8)	Drug Discovery & Target-based drug discovery approaches
9)	System biology and Network Analysis I
10)	Egyptian Mythology and Thalamus, Pineal 2
11)	Elucidating the disease mechanism through computational approaches
12)	Translational medicine: How to integrate data into treatment alternatives?
13)	Review & Project presentations
14)	Review & Project presentations

Sources

Course Notes / Textbooks:	ders çıktıları-lecturer lesson
References:	Biyoinformatik temelleri ve uygulamaları (Mehmet Cengiz Baloğlu)

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5
Program Outcomes
1) When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.
2) knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.
3) is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.
4) knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.
5) can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.
6) knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7) can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8) knows the clinical decision-making process, evidence-based medicine practices and current approaches.
9) knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10) knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11) is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12) knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.
13) can collect health data, analyze them, present them in summary, and prepare forensic reports.
14) knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.
15) knows employee health, environment and occupational safety issues and takes responsibility when necessary.
16) knows health policies and is able to evaluate their effects in the field of application.
17) keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.
18) applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.
2)	knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.
3)	is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.
4)	knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.
5)	can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.
6)	knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7)	can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8)	knows the clinical decision-making process, evidence-based medicine practices and current approaches.
9)	knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10)	knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11)	is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12)	knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.
13)	can collect health data, analyze them, present them in summary, and prepare forensic reports.
14)	knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.
15)	knows employee health, environment and occupational safety issues and takes responsibility when necessary.
16)	knows health policies and is able to evaluate their effects in the field of application.
17)	keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.
18)	applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	1	% 20
Midterms	1	% 30
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	2	0	1	15	32
Application	1	0			0
Study Hours Out of Class	1	0	1	1	2
Presentations / Seminar	1	1	2	4	7
Midterms	1	2	2	1	5
Final	1	2	2	1	5
Total Workload					51