Medicine Preview
Bachelor	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Course Introduction and Application Information

Course Code:

TIP042

Course Name:

Genome Organization

Semester:

Fall
Spring

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

Bachelor

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

E-Learning

Course Coordinator:

Prof. Dr. VEYSEL SABRİ HANÇER

Course Lecturer(s):

Prof.Dr.Veysel Sabri Hançer

Course Assistants:

Course Objective and Content

Course Objectives:	Learning human gene and genome structure
Course Content:	Definition of gene and genome. Structure and organization of DNA in eukaryotes. Gene and genome structure and organization in eukaryotes.

Learning Outcomes

The students who have succeeded in this course;
1) Learns gene structure and organization of eukaryotic organisms.
2) Understand the functions of the DNA molecule that makes up the gene
3) Recognizes different genomes, learns their structure and organization

Course Flow Plan

Week	Subject	Related Preparation
1)	The structure and functions of DNA
2)	Gene, definition and general structure
3)	Genome definition and general structure, organizational mechanisms
4)	Different genomes in eukaryotic organisms
5)	Coding regions in the nuclear genome
6)	Non-coding regions in the nuclear genome
7)	Repetitive regions in the genome, their location, importance and functions
8)	Pseudogenes
9)	Satellite DNA
10)	Minisatellites
11)	Microsatellites
12)	LINE regions
13)	SINE regions
14)	Long non-coding RNAs
15)	Transposons
16)	Telomeric DNA

Sources

Course Notes / Textbooks:	Molecular Biology of the Gene (Ed: Watson Baker, Bell Gann, Lewine Losick) Molecular Biology (Ed: David P. Clark) Genes IX (Ed: Benjamin Lewin) Moleküler Biyoloji (Ed: Ahmet Yıldırım, Fevzi Bardakçı, Mehmet Karataş, Bahattin Tanyolaç)
References:	Genomes. 2nd edition. Brown TA. Oxford: Wiley-Liss; 2002.

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3
Program Outcomes
1) When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.
2) knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.
3) is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.
4) knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.
5) can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.
6) knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7) can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8) knows the clinical decision-making process, evidence-based medicine practices and current approaches.
9) knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10) knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11) is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12) knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.
13) can collect health data, analyze them, present them in summary, and prepare forensic reports.
14) knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.
15) knows employee health, environment and occupational safety issues and takes responsibility when necessary.
16) knows health policies and is able to evaluate their effects in the field of application.
17) keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.
18) applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.
2)	knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.
3)	is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.
4)	knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.
5)	can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.
6)	knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7)	can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8)	knows the clinical decision-making process, evidence-based medicine practices and current approaches.
9)	knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10)	knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11)	is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12)	knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.
13)	can collect health data, analyze them, present them in summary, and prepare forensic reports.
14)	knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.
15)	knows employee health, environment and occupational safety issues and takes responsibility when necessary.
16)	knows health policies and is able to evaluate their effects in the field of application.
17)	keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.
18)	applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Attendance	1	% 20
Application	1	% 10
Homework Assignments	1	% 50
Presentation	1	% 20
total		% 100
PERCENTAGE OF SEMESTER WORK		% 100
PERCENTAGE OF FINAL WORK		%
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	16	0			0
Study Hours Out of Class	48	0			0
Presentations / Seminar	16	0			0
Homework Assignments	16	0			0
Total Workload					0