Stem Cell and Tissue Engineering (Master) (with Thesis) Preview
Master	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Course Introduction and Application Information

Course Code:

KHY5113

Course Name:

Transgenic Animal Models and Production

Semester:

Spring

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

Master

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator:

Dr. Öğr. Üy. AYŞE KÖYLÜ

Course Lecturer(s):

Hakan DARICI

Course Assistants:

Course Objective and Content

Course Objectives:	To give theoretical information about the production of transgenic living things by making genetic changes in animals and cells.
Course Content:	Reproductive cycle in humans, mice and rabbits, egg collection methods and hormones used, vasectomy operation in mice, embryo classification, culture and gene transfer. Different gene transfer techniques and genetically modified organisms.

Learning Outcomes

The students who have succeeded in this course;
1) Knows the reproductive cycle and early embryo development in humans and rodents.
2) Knows culture methods by collecting eggs and embryos with assisted reproductive techniques.
3) Knows the methods used for gene transfer in egg, embryo, and adult cells.
4) Knows how and when existing and developing gene transfer methods can be used.

Course Flow Plan

Week	Subject	Related Preparation
1)	Genetically modified organisms (GMO), transgenic animals and definition of gene exchange
2)	History of GMO and the first studies
3)	Human reproductive cycle and fertilization
4)	Reproductive cycle and fertilization in rodents
5)	Egg collection techniques, tools and hormones
6)	Vasectomy animal breeding and mating
7)	Embryo collection and culture
8)	Gene transfer methods in the embryo
9)	Gene transfer methods in adults
10)	Gene modification in cell culture
11)	Gene modification today
12)	Presentations - I
13)	Presentations - II
14)	Presentations - III
15)	Final exam

Sources

Course Notes / Textbooks:	Öğretim üyesine ait ders notları
References:	Öğretim üyesine ait ders notları

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4
Program Outcomes
1) Being able to develop and deepen their knowledge in the same or a different field at the level of expertise, based on their undergraduate level qualifications.	3	3	3	3
2) To be able to comprehend the interdisciplinary interaction with which the field is related.			1
3) To be able to use the theoretical and applied knowledge at the level of expertise acquired in the field.	3	3	3	3
4) To be able to interpret and create new knowledge by integrating the knowledge gained in the field with the knowledge from different disciplines,	1		2
5) To be able to solve the problems encountered in the field by using research methods.	1
6) Being able to independently carry out a work that requires expertise in the field.	3	3	3	3
7) To be able to develop new strategic approaches for the solution of complex and unpredictable problems encountered in applications related to the field and to produce solutions by taking responsibility.	3	3	3	3
8) To be able to lead in environments that require the resolution of problems related to the field.	1
9) To be able to critically evaluate the knowledge and skills acquired in the field of expertise and to direct their learning.			1
10) To be able to systematically transfer the current developments in the field and their own studies to groups in and outside the field, in written, verbal and visual forms, by supporting them with quantitative and qualitative data.	3	3	3	3
11) To be able to critically examine and develop social relations and the norms that guide these relations, and to take action to change them when necessary.				1
12) To be able to communicate orally and in writing using a foreign language at least at the B2 General Level of the European Language Portfolio.	1		1
13) To be able to use information and communication technologies at an advanced level, together with computer software at the level required by the field.	1		2
14) To be able to supervise and teach these values by observing social, scientific, cultural and ethical values in the stages of collecting, interpreting, applying and announcing the data related to the field.		1
15) To be able to develop strategy, policy and implementation plans on issues related to his field and to evaluate the results obtained within the framework of quality processes.				2
16) To be able to use the knowledge, problem solving and/or application skills they have internalized in the field, in interdisciplinary studies.	3	3	3	3

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	Being able to develop and deepen their knowledge in the same or a different field at the level of expertise, based on their undergraduate level qualifications.	2
2)	To be able to comprehend the interdisciplinary interaction with which the field is related.	2
3)	To be able to use the theoretical and applied knowledge at the level of expertise acquired in the field.	2
4)	To be able to interpret and create new knowledge by integrating the knowledge gained in the field with the knowledge from different disciplines,	2
5)	To be able to solve the problems encountered in the field by using research methods.	2
6)	Being able to independently carry out a work that requires expertise in the field.	2
7)	To be able to develop new strategic approaches for the solution of complex and unpredictable problems encountered in applications related to the field and to produce solutions by taking responsibility.	3
8)	To be able to lead in environments that require the resolution of problems related to the field.	2
9)	To be able to critically evaluate the knowledge and skills acquired in the field of expertise and to direct their learning.	2
10)	To be able to systematically transfer the current developments in the field and their own studies to groups in and outside the field, in written, verbal and visual forms, by supporting them with quantitative and qualitative data.	2
11)	To be able to critically examine and develop social relations and the norms that guide these relations, and to take action to change them when necessary.	2
12)	To be able to communicate orally and in writing using a foreign language at least at the B2 General Level of the European Language Portfolio.	3
13)	To be able to use information and communication technologies at an advanced level, together with computer software at the level required by the field.	3
14)	To be able to supervise and teach these values by observing social, scientific, cultural and ethical values in the stages of collecting, interpreting, applying and announcing the data related to the field.	2
15)	To be able to develop strategy, policy and implementation plans on issues related to his field and to evaluate the results obtained within the framework of quality processes.	2
16)	To be able to use the knowledge, problem solving and/or application skills they have internalized in the field, in interdisciplinary studies.	3

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Presentation	1	% 50
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Workload
Course Hours	16	48
Study Hours Out of Class	16	64
Presentations / Seminar	1	3
Final	1	3
Total Workload		118