| Medical Biology and Genetics (DR) | |||||
| PhD | TR-NQF-HE: Level 8 | QF-EHEA: Third Cycle | EQF-LLL: Level 8 | ||
| Course Code: | TGY6104 | ||||
| Course Name: | Molecular Basis of Diseases | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Dr. Öğr. Üy. YEMLİHA YILDIZ | ||||
| Course Lecturer(s): | Dr. Yemliha Yıldız | ||||
| Course Assistants: |
| Course Objectives: | The aim of this course for each student; To have knowledge about the molecular mechanisms underlying diseases |
| Course Content: | In this course, students acquire basic knowledge about the molecular pathogenesis of diseases. |
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The students who have succeeded in this course;
1) List the general molecular mechanisms that cause diseases. 2) Discusses the hereditary mechanisms that cause diseases. 3) Explain the pathophysiology of hereditary diseases. 4) Lists the general molecular mechanisms that cause cancer. 5) List the genetic mechanisms that cause cancer. 6) Explain the epigenetic mechanisms that cause cancer. |
| Week | Subject | Related Preparation |
| 1) | General mechanisms of diseases | MOLECULAR BİOLOGY OF THE CELL 6E, BRUCE ALBERTS |
| 2) | Molecular mechanisms of disases-I | ROBBİNS BASİC PATHOLOGY (ROBBİNS PATHOLOGY), VİNAY KUMAR MBBS MD FRCPATH, ABUL K. ABBAS MBBS, JON C. ASTER MD PHD |
| 3) | Molecular mechanisms of disases-II | - ROBBİNS BASİC PATHOLOGY (ROBBİNS PATHOLOGY), VİNAY KUMAR MBBS MD FRCPATH, ABUL K. ABBAS MBBS, JON C. ASTER MD PHD |
| 4) | Immunity, inflammation, shock and sepsis | ROBBİNS BASİC PATHOLOGY (ROBBİNS PATHOLOGY), VİNAY KUMAR MBBS MD FRCPATH, ABUL K. ABBAS MBBS, JON C. ASTER MD PH |
| 5) | Student presentation | |
| 6) | Student presentation | |
| 7) | Student presentation | |
| 8) | Student presentation | |
| 9) | Student presentation | |
| 10) | Student presentation | |
| 11) | Cancer | THE BIOLOGY OF CANCER, ROBERT A. WEINBERG |
| 12) | Molecular basis of cancer | THE BIOLOGY OF CANCER, ROBERT A. WEINBERG |
| 13) | Epigenetic basis of cancer | THE BIOLOGY OF CANCER, ROBERT A. WEINBERG |
| 14) | Genetic basis of cancer | THE BIOLOGY OF CANCER, ROBERT A. WEINBERG |
| Course Notes / Textbooks: | Dersle İlgili hazırlanan sunumlar, ilgili konuya ilişkin önemli ve güncel makaleler |
| References: | - MOLECULAR BİOLOGY OF THE CELL 6E, BRUCE ALBERTS ALEXANDER JOHNSON JULİAN LEWİS, MARTİN RAFF, KEITH ROBERTS AND PETER WALTER - THE BIOLOGY OF CANCER, ROBERT A. WEINBERG - HARRİSON'S PRİNCİPLES OF INTERNAL MEDİCİNE, DENNİS L. KASPER ANTHONY S. FAUCİ STEPHEN L. HAUSER DAN L. LONGO J. LARRY JAMESON, JOSEPH LOSCALZO - ROBBİNS BASİC PATHOLOGY (ROBBİNS PATHOLOGY), VİNAY KUMAR MBBS MD FRCPATH, ABUL K. ABBAS MBBS, JON C. ASTER MD PHD |
| Course Learning Outcomes | 1 |
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3 |
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5 |
6 |
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| Program Outcomes | |||||||
| 1) Follows the current literature in the field of Medical Biology and Genetics, collects information, analyzes and synthesizes it with appropriate evaluation methods and guides clinical practices. | |||||||
| 2) Uses appropriate methods and technological structures for scientific research, establishes the appropriate hypothesis, and determines research methods. | |||||||
| 3) Interprets the results obtained as a result of scientific research, transfers and develops the evidence-based knowledge obtained into applications, presents its results at national and international scientific meetings and publishes them in peer-reviewed journals. | |||||||
| 4) Realizes the principles of lifelong learning by observing professional autonomy within the ethical, deontological and legal framework in Medical Biology and Genetics applications and scientific studies. | |||||||
| 5) Provides interdisciplinary collaboration in academic and clinical environments and has knowledge and skills in problem solving and management. | |||||||
| 6) Uses the information obtained from scientific research and literature for the benefit of society and ensures the shaping of health policies necessary to improve public health and takes part in these policies. | |||||||
| 7) Trains biologists who combine clinical experience and academic knowledge, produce, plan and implement creative solutions in the field of medical biology and have qualified knowledge and skills. | |||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Follows the current literature in the field of Medical Biology and Genetics, collects information, analyzes and synthesizes it with appropriate evaluation methods and guides clinical practices. | 2 |
| 2) | Uses appropriate methods and technological structures for scientific research, establishes the appropriate hypothesis, and determines research methods. | |
| 3) | Interprets the results obtained as a result of scientific research, transfers and develops the evidence-based knowledge obtained into applications, presents its results at national and international scientific meetings and publishes them in peer-reviewed journals. | |
| 4) | Realizes the principles of lifelong learning by observing professional autonomy within the ethical, deontological and legal framework in Medical Biology and Genetics applications and scientific studies. | |
| 5) | Provides interdisciplinary collaboration in academic and clinical environments and has knowledge and skills in problem solving and management. | |
| 6) | Uses the information obtained from scientific research and literature for the benefit of society and ensures the shaping of health policies necessary to improve public health and takes part in these policies. | |
| 7) | Trains biologists who combine clinical experience and academic knowledge, produce, plan and implement creative solutions in the field of medical biology and have qualified knowledge and skills. | 1 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Presentation | 1 | % 40 |
| Final Pratik | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 100 | |
| PERCENTAGE OF FINAL WORK | % | |
| total | % 100 | |
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 56 |
| Study Hours Out of Class | 10 | 50 |
| Presentations / Seminar | 7 | 30 |
| Homework Assignments | 5 | 5 |
| Final | 2 | 11 |
| Total Workload | 152 | |