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Associate	TR-NQF-HE: Level 5	QF-EHEA: Short Cycle	EQF-LLL: Level 5

Course Introduction and Application Information

Course Code:

UNI261

Course Name:

Regenerative Biology and Medicine Applications

Semester:

Spring

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Type of course:

University Elective

Course Level:

Associate

TR-NQF-HE:5. Master`s Degree

QF-EHEA:Short Cycle

EQF-LLL:5. Master`s Degree

Mode of Delivery:

E-Learning

Course Coordinator:

Dr. Öğr. Üy. ASLI PINAR ZORBA YILDIZ

Course Lecturer(s):

Aslı Pınar Zorba Yıldız

Course Assistants:

Course Objective and Content

Course Objectives:	The aim of this course is to learn about regenerative biology, evaluation of tissues, wounds or immune processes such as antibody-vaccine that cannot be performed using today's technology, current treatment approaches, biomaterials used and 3D bioprinter systems, and learning the age-appropriate information and ways to reach information suitable for 21st century skills.
Course Content:	The content of this course includes current uses of regenerative biology in various treatments with today's technology and how it will be carried forward with new generation technologies in the future, various legal regulations and good laboratory practices.

Learning Outcomes

The students who have succeeded in this course;
1) Explains the concept of regenerative biology and compares it with examples in nature.
2) Classifies treatment methods that fall into the field of regenerative medicine.
3) Compares stem cell and somatic cell systems and their application areas.
4) Explain the basic principles of tissue engineering, biomaterials and application areas.
5) Explains transplantation processes, stem cell vaccines and immune response.
6) Explains artificial tissue engineering application areas and processes according to systems.
7) Explains and classifies nanotechnological approaches and cloning.
8) Explains working principles and legal regulations under GMP conditions.

Course Flow Plan

Week	Subject	Related Preparation
1)	History, Medical Purpose and Importance of Regenerative Biology
2)	Cloning Technology: Therapeutic and Reproductive Cloning
3)	Somatic Cell Culture Basic Principles and Applications
4)	Stem Cell Systems, Types and Application Areas
5)	Exosome Technology and Applications
6)	Antibody Engineering and Stem Cell Vaccines
7)	Midterm
8)	Basic Tissue Engineering, Cell and Tissue Transplantation and Immunity
9)	Biomaterials Used in Regenerative Medicine and Their Properties
10)	Artificial Tissue Engineering with 3-D Printers
11)	Musculoskeletal System, Diabetes and Islet Regenerative Medicine Applications
12)	Central and Peripheral Nervous System Regenerative Medicine Applications
13)	Nanobiotechnology Introduction, Nanorobotic Systems and Pharmaceutical Applications
14)	GMP (Good Manufacturing Practice) Technology, Working Areas, Legal Regulations
15)	Final
16)	Final

Sources

Course Notes / Textbooks:	• Alp Can, Kök Hücre, Akademisyen Kitapevi • Prof. Dr. Adil M. Allahverdiyev , Somatik ve Kök Hücre Kültür Sistemlerinin Temel İlkeleri, Nobel Tıp Kitapevleri • Michael A. Palladino, William J. Thieman, Biyoteknolojiye Giriş, Palme Yayıncılık • Steven R. Goodman , Goodman's Medical Cell Biology, 4th Edition, Elsevier
References:	• Alp Can, Kök Hücre, Akademisyen Kitapevi • Prof. Dr. Adil M. Allahverdiyev , Somatik ve Kök Hücre Kültür Sistemlerinin Temel İlkeleri, Nobel Tıp Kitapevleri • Michael A. Palladino, William J. Thieman, Biyoteknolojiye Giriş, Palme Yayıncılık • Steven R. Goodman , Goodman's Medical Cell Biology, 4th Edition, Elsevier

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5	6	7	8
Program Outcomes
1) Has basic knowledge about radiotherapy, basic oncology, radiological imaging
2) Has the ability to use tools, devices and techniques related to the field in public and private health institutions.
3) Takes responsibility as a team member in solving unforeseen and complex problems encountered in applications related to the field.
4) Knows the effects of radiation on biological systems and takes necessary measures for protection against radiation for patients and employees.
5) Use medical imaging systems related to the field and evaluate the images taken.
6) Professionals, patients, patient relatives and other health care professionals communicate effectively when practicing their profession.
7) Keeps track of the data related to the studies done in the field and analyzes the data with the latest methods
8) It follows information in the field by using a foreign language at least at the level of European Language Portfolio A2 General Level.
9) Uses information and communication technologies together with computer software at the basic level of at least European Computer Driving License required by the field.
10) Carries out routine controls of the devices and equipment used in the practice of his / her job and follow-up of the work where necessary (fault, maintenance).
11) The student can transfer the current and updated information about the profession by means of written and verbal communication.
12) Has the basic knowledge, ethical principles and acts in accordance with the laws, regulations and legislation related to his / her profession.
13) Has experience in working with other fields that may be related to the field.
14) Has awareness of lifelong learning.
15) Contributes to projects and activities for the social environment he lives in with the awareness of social responsibility and sets an example for the society with his external appearance.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	Has basic knowledge about radiotherapy, basic oncology, radiological imaging
2)	Has the ability to use tools, devices and techniques related to the field in public and private health institutions.
3)	Takes responsibility as a team member in solving unforeseen and complex problems encountered in applications related to the field.
4)	Knows the effects of radiation on biological systems and takes necessary measures for protection against radiation for patients and employees.
5)	Use medical imaging systems related to the field and evaluate the images taken.
6)	Professionals, patients, patient relatives and other health care professionals communicate effectively when practicing their profession.
7)	Keeps track of the data related to the studies done in the field and analyzes the data with the latest methods
8)	It follows information in the field by using a foreign language at least at the level of European Language Portfolio A2 General Level.
9)	Uses information and communication technologies together with computer software at the basic level of at least European Computer Driving License required by the field.
10)	Carries out routine controls of the devices and equipment used in the practice of his / her job and follow-up of the work where necessary (fault, maintenance).
11)	The student can transfer the current and updated information about the profession by means of written and verbal communication.
12)	Has the basic knowledge, ethical principles and acts in accordance with the laws, regulations and legislation related to his / her profession.
13)	Has experience in working with other fields that may be related to the field.
14)	Has awareness of lifelong learning.
15)	Contributes to projects and activities for the social environment he lives in with the awareness of social responsibility and sets an example for the society with his external appearance.

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	1	% 5
Presentation	1	% 5
Project	1	% 20
Midterms	1	% 20
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	2	14			28
Presentations / Seminar	1	20			20
Project	1	20			20
Homework Assignments	2	10			20
Midterms	1	10			10
Final	1	16			16
Total Workload					114