Dentistry
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code: UNI261
Course Name: Regenerative Biology and Medicine Applications
Semester: Spring
Course Credits:
ECTS
5
Language of instruction: Turkish
Course Condition:
Does the Course Require Work Experience?: No
Type of course: University Elective
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: E-Learning
Course Coordinator: Dr. Öğr. Üy. ASLI PINAR ZORBA YILDIZ
Course Lecturer(s): Aslı Pınar Zorba Yıldız
Course Assistants:

Course Objective and Content

Course Objectives: The aim of this course is to learn about regenerative biology, evaluation of tissues, wounds or immune processes such as antibody-vaccine that cannot be performed using today's technology, current treatment approaches, biomaterials used and 3D bioprinter systems, and learning the age-appropriate information and ways to reach information suitable for 21st century skills.
Course Content: The content of this course includes current uses of regenerative biology in various treatments with today's technology and how it will be carried forward with new generation technologies in the future, various legal regulations and good laboratory practices.

Learning Outcomes

The students who have succeeded in this course;
1) Explains the concept of regenerative biology and compares it with examples in nature.
2) Classifies treatment methods that fall into the field of regenerative medicine.
3) Compares stem cell and somatic cell systems and their application areas.
4) Explain the basic principles of tissue engineering, biomaterials and application areas.
5) Explains transplantation processes, stem cell vaccines and immune response.
6) Explains artificial tissue engineering application areas and processes according to systems.
7) Explains and classifies nanotechnological approaches and cloning.
8) Explains working principles and legal regulations under GMP conditions.

Course Flow Plan

Week Subject Related Preparation
1) History, Medical Purpose and Importance of Regenerative Biology
2) Cloning Technology: Therapeutic and Reproductive Cloning
3) Somatic Cell Culture Basic Principles and Applications
4) Stem Cell Systems, Types and Application Areas
5) Exosome Technology and Applications
6) Antibody Engineering and Stem Cell Vaccines
7) Midterm
8) Basic Tissue Engineering, Cell and Tissue Transplantation and Immunity
9) Biomaterials Used in Regenerative Medicine and Their Properties
10) Artificial Tissue Engineering with 3-D Printers
11) Musculoskeletal System, Diabetes and Islet Regenerative Medicine Applications
12) Central and Peripheral Nervous System Regenerative Medicine Applications
13) Nanobiotechnology Introduction, Nanorobotic Systems and Pharmaceutical Applications
14) GMP (Good Manufacturing Practice) Technology, Working Areas, Legal Regulations
15) Final
16) Final

Sources

Course Notes / Textbooks: • Alp Can, Kök Hücre, Akademisyen Kitapevi
• Prof. Dr. Adil M. Allahverdiyev , Somatik ve Kök Hücre Kültür Sistemlerinin Temel İlkeleri, Nobel Tıp Kitapevleri
• Michael A. Palladino, William J. Thieman, Biyoteknolojiye Giriş, Palme Yayıncılık
• Steven R. Goodman , Goodman's Medical Cell Biology, 4th Edition, Elsevier
References: • Alp Can, Kök Hücre, Akademisyen Kitapevi
• Prof. Dr. Adil M. Allahverdiyev , Somatik ve Kök Hücre Kültür Sistemlerinin Temel İlkeleri, Nobel Tıp Kitapevleri
• Michael A. Palladino, William J. Thieman, Biyoteknolojiye Giriş, Palme Yayıncılık
• Steven R. Goodman , Goodman's Medical Cell Biology, 4th Edition, Elsevier

Course - Program Learning Outcome Relationship

Course Learning Outcomes

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8

Program Outcomes
1) Has basic and up-to-date knowledge in the field of dentistry, follows scientific publications, and applies evidence-based data to his/her professional practice.
2) Knows well and effectively uses devices, tools, and materials specific to diagnosis and treatment in the field of dentistry.
3) Evaluates the knowledge in the field of dentistry critically, integrates it with the knowledge of disciplines in the field of health, uses it by analyzing and synthesizing it.
4) Produces projects related to the field of dentistry, can work with other health disciplines, takes part as a member of the research team and evaluates and reports the results obtained at a scientific level.
5) Uses information that will contribute to the dentistry profession during practice, takes responsibility, and produces solutions in unforeseen situations.
6) Shares, compares, and exchanges dental knowledge with professional colleagues in social and scientific environments in written, verbal, and visual forms.
7) Within the framework of social, scientific, and ethical values including patient privacy, communicates with patients and their relatives, knows all the characteristics of the patient, and recommends the most appropriate treatment with a patient-centered approach.
8) Follows technological developments, participates in national and international studies, and shares and presents own observations, experiences, and research to further advance dental practices.
9) By adopting the principle of lifelong learning throughout the dentistry profession, follows current evidence-based dental knowledge and uses it during his professional practice.
10) During dental practice, in cases such as abuse and addiction, performs the treatment by exhibiting the behaviors required by social ethics and legal rules, and collects and records the relevant data.
11) Uses basic and current knowledge in the field of dentistry during professional practice for the benefit of society within the framework of national values and country realities.
12) In natural disasters and emergency cases, takes the protective measures required by the dentistry profession; performs professional practices that benefit patients and society
13) Generates ideas regarding health policy in dentistry, prioritizes individual and public health, and carries out preventive and therapeutic medical practices within the framework of scientific, ethical, and quality processes.
14) Differentiates the signs and symptoms commonly encountered in the dentistry profession, makes a treatment plan and refers when necessary, and manages diseases and clinical situations regarding their urgency and patient priority.
15) Can assume the leadership responsibility of the team he/she works for, manage it following scientific criteria, and support the professional development of the team.

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Average 3 Highest
       
Program Outcomes Level of Contribution
1) Has basic and up-to-date knowledge in the field of dentistry, follows scientific publications, and applies evidence-based data to his/her professional practice.
2) Knows well and effectively uses devices, tools, and materials specific to diagnosis and treatment in the field of dentistry.
3) Evaluates the knowledge in the field of dentistry critically, integrates it with the knowledge of disciplines in the field of health, uses it by analyzing and synthesizing it.
4) Produces projects related to the field of dentistry, can work with other health disciplines, takes part as a member of the research team and evaluates and reports the results obtained at a scientific level.
5) Uses information that will contribute to the dentistry profession during practice, takes responsibility, and produces solutions in unforeseen situations.
6) Shares, compares, and exchanges dental knowledge with professional colleagues in social and scientific environments in written, verbal, and visual forms.
7) Within the framework of social, scientific, and ethical values including patient privacy, communicates with patients and their relatives, knows all the characteristics of the patient, and recommends the most appropriate treatment with a patient-centered approach.
8) Follows technological developments, participates in national and international studies, and shares and presents own observations, experiences, and research to further advance dental practices.
9) By adopting the principle of lifelong learning throughout the dentistry profession, follows current evidence-based dental knowledge and uses it during his professional practice.
10) During dental practice, in cases such as abuse and addiction, performs the treatment by exhibiting the behaviors required by social ethics and legal rules, and collects and records the relevant data.
11) Uses basic and current knowledge in the field of dentistry during professional practice for the benefit of society within the framework of national values and country realities.
12) In natural disasters and emergency cases, takes the protective measures required by the dentistry profession; performs professional practices that benefit patients and society
13) Generates ideas regarding health policy in dentistry, prioritizes individual and public health, and carries out preventive and therapeutic medical practices within the framework of scientific, ethical, and quality processes.
14) Differentiates the signs and symptoms commonly encountered in the dentistry profession, makes a treatment plan and refers when necessary, and manages diseases and clinical situations regarding their urgency and patient priority.
15) Can assume the leadership responsibility of the team he/she works for, manage it following scientific criteria, and support the professional development of the team.

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Homework Assignments 1 % 5
Presentation 1 % 5
Project 1 % 20
Midterms 1 % 20
Final 1 % 50
total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
total % 100

Workload and ECTS Credit Calculation

Activities Number of Activities Preparation for the Activity Spent for the Activity Itself Completing the Activity Requirements Workload
Course Hours 2 14 28
Presentations / Seminar 1 20 20
Project 1 20 20
Homework Assignments 2 10 20
Midterms 1 10 10
Final 1 16 16
Total Workload 114