| Stem Cell And Tissue Engineering (DR) | |||||
| PhD | TR-NQF-HE: Level 8 | QF-EHEA: Third Cycle | EQF-LLL: Level 8 | ||
| Course Code: | KHDD6102 | ||||
| Course Name: | Advanced Stem Cell Biology | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | |||||
| Course Coordinator: | Dr. Öğr. Üy. AYŞE KÖYLÜ | ||||
| Course Lecturer(s): | Erdal Karaöz | ||||
| Course Assistants: |
| Course Objectives: | Within the scope of this course, clinical practices will be covered together with ethical discussions and legal regulations. In addition, the characteristic features, effective intracellular pathways and differentiation of Mesenchymal Stem Cells, Hematopoietic Stem Cells and further differentiated unipotent stem cells in adult individuals will be learned. |
| Course Content: | In this course, the characteristic features, effective intracellular pathways and differentiation of Mesenchymal Stem Cells, Hematopoietic Stem Cells and further differentiated unipotent stem cells in adults will be explained. In addition, isolation, characterization, culture and differentiation processes of these cells will be explained. |
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The students who have succeeded in this course;
1) Students will have acquired information about stem cells and stem cell types. 2) Students will have learned the differentiation of cells and their molecular pathways. 3) Students will have learned the use of stem cells in the clinic. 4) Students will have learned the isolation and characterization techniques of Cells. 5) Students will have gained competence about stem cell culture techniques. |
| Week | Subject | Related Preparation |
| 1) | What is stem cell biology? Its scope and objectives, Classification of stem cells | |
| 2) | What is embryonic stem cell? What is IPCS? Identification and uses of embryonic stem cells | |
| 3) | What is an adult stem cell? Types of adult stem cells What is a mesenchymal stem cell? What are the usage areas? | |
| 4) | Stem cell isolation and clinical applications | |
| 5) | What is a hematopoietic stem cell? Cord blood banking | |
| 6) | Characterization of mesenchymal cells by fluorescent methods | |
| 7) | General Review and Q&A | |
| 8) | Student presentations | |
| 9) | Use of stem cells in renewable therapy and tissue engineering | |
| 10) | Use of stem cells in gene therapies | |
| 11) | Production of stem cells under GMP conditions | |
| 12) | Adult Stem Cell Therapies in clinical trials settings | |
| 13) | Stem cell biomarkers in health and disease conditions | |
| 14) | Final Exam |
| Course Notes / Textbooks: | Kök Hücre, Alp CAN |
| References: | Essentials of Stem Cell Biology: Robert Lanza |
| Course Learning Outcomes | 1 |
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| Program Outcomes | ||||||||||||||||
| 1) To be able to develop and deepen current and advanced knowledge in the field with original thought and / or research at the level of expertise based on master's qualifications and to reach original definitions that will bring innovation to the field. | ||||||||||||||||
| 2) To be able to comprehend the interdisciplinary interaction that the field is related to; Ability to reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | ||||||||||||||||
| 3) To be able to evaluate and use new knowledge in the field with a systematic approach. | ||||||||||||||||
| 4) To be able to develop a new idea, method, design and/or application that brings innovation to the field, or to apply a known idea, method, design and/or application to a different field, to research, comprehend, design, adapt and apply an original subject. | ||||||||||||||||
| 5) To be able to critically analyze, synthesize and evaluate new and complex ideas. | ||||||||||||||||
| 6) Gaining high-level skills in using research methods in studies related to the field. | ||||||||||||||||
| 7) Being able to contribute to the progress in the field by independently carrying out an original work that brings innovations to the field, develops a new idea, method, design and / or application or applies a known idea, method, design and / or application to a different field. | ||||||||||||||||
| 8) To be able to expand the limits of knowledge in the field by publishing at least one scientific article related to the field in national and/or international refereed journals and/or by producing or interpreting an original work. | ||||||||||||||||
| 9) Ability to lead in environments that require the resolution of unique and interdisciplinary problems. | ||||||||||||||||
| 10) To be able to develop new thoughts and methods in the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. | ||||||||||||||||
| 11) To be able to critically examine and develop social relations and the norms that guide these relations, and to manage actions to change them when necessary. | ||||||||||||||||
| 12) To be able to defend their original views in the discussion of the issues in the field with experts and to establish an effective communication showing their competence in the field. | ||||||||||||||||
| 13) To be able to communicate and discuss at an advanced level in written, oral and visual using a foreign language at least at the C1 General Level of the European Language Portfolio. | ||||||||||||||||
| 14) To be able to contribute to the process of becoming an information society and maintaining it by introducing scientific, technological, social or cultural advances in the field. | ||||||||||||||||
| 15) To be able to interact functionally by using strategic decision-making processes in solving the problems encountered in the field. | ||||||||||||||||
| 16) To be able to contribute to the solution of social, scientific, cultural and ethical problems encountered in the fields related to the field and to support the development of these values. | ||||||||||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | To be able to develop and deepen current and advanced knowledge in the field with original thought and / or research at the level of expertise based on master's qualifications and to reach original definitions that will bring innovation to the field. | 3 |
| 2) | To be able to comprehend the interdisciplinary interaction that the field is related to; Ability to reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. | 3 |
| 3) | To be able to evaluate and use new knowledge in the field with a systematic approach. | 3 |
| 4) | To be able to develop a new idea, method, design and/or application that brings innovation to the field, or to apply a known idea, method, design and/or application to a different field, to research, comprehend, design, adapt and apply an original subject. | 3 |
| 5) | To be able to critically analyze, synthesize and evaluate new and complex ideas. | 2 |
| 6) | Gaining high-level skills in using research methods in studies related to the field. | 2 |
| 7) | Being able to contribute to the progress in the field by independently carrying out an original work that brings innovations to the field, develops a new idea, method, design and / or application or applies a known idea, method, design and / or application to a different field. | 3 |
| 8) | To be able to expand the limits of knowledge in the field by publishing at least one scientific article related to the field in national and/or international refereed journals and/or by producing or interpreting an original work. | 3 |
| 9) | Ability to lead in environments that require the resolution of unique and interdisciplinary problems. | 2 |
| 10) | To be able to develop new thoughts and methods in the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. | 2 |
| 11) | To be able to critically examine and develop social relations and the norms that guide these relations, and to manage actions to change them when necessary. | 3 |
| 12) | To be able to defend their original views in the discussion of the issues in the field with experts and to establish an effective communication showing their competence in the field. | 2 |
| 13) | To be able to communicate and discuss at an advanced level in written, oral and visual using a foreign language at least at the C1 General Level of the European Language Portfolio. | 1 |
| 14) | To be able to contribute to the process of becoming an information society and maintaining it by introducing scientific, technological, social or cultural advances in the field. | 3 |
| 15) | To be able to interact functionally by using strategic decision-making processes in solving the problems encountered in the field. | 3 |
| 16) | To be able to contribute to the solution of social, scientific, cultural and ethical problems encountered in the fields related to the field and to support the development of these values. | 2 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 40 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
| Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
| Course Hours | 14 | 10 | 140 | ||||
| Midterms | 1 | 6 | 1 | 7 | |||
| Final | 1 | 8 | 1 | 9 | |||
| Total Workload | 156 | ||||||