Histology and Embryology (DR) Preview
PhD	TR-NQF-HE: Level 8	QF-EHEA: Third Cycle	EQF-LLL: Level 8

Course Introduction and Application Information

Course Code:

KHDD6102

Course Name:

Advanced Stem Cell Biology

Semester:

Fall
Spring

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

PhD

TR-NQF-HE:8. Master`s Degree

QF-EHEA:Third Cycle

EQF-LLL:8. Master`s Degree

Mode of Delivery:

Course Coordinator:

Dr. Öğr. Üy. AYŞE KÖYLÜ

Course Lecturer(s):

Erdal Karaöz

Course Assistants:

Course Objective and Content

Course Objectives:	Within the scope of this course, clinical practices will be covered together with ethical discussions and legal regulations. In addition, the characteristic features, effective intracellular pathways and differentiation of Mesenchymal Stem Cells, Hematopoietic Stem Cells and further differentiated unipotent stem cells in adult individuals will be learned.
Course Content:	In this course, the characteristic features, effective intracellular pathways and differentiation of Mesenchymal Stem Cells, Hematopoietic Stem Cells and further differentiated unipotent stem cells in adults will be explained. In addition, isolation, characterization, culture and differentiation processes of these cells will be explained.

Learning Outcomes

The students who have succeeded in this course;
1) Students will have acquired information about stem cells and stem cell types.
2) Students will have learned the differentiation of cells and their molecular pathways.
3) Students will have learned the use of stem cells in the clinic.
4) Students will have learned the isolation and characterization techniques of Cells.
5) Students will have gained competence about stem cell culture techniques.

Course Flow Plan

Week	Subject	Related Preparation
1)	What is stem cell biology? Its scope and objectives, Classification of stem cells
2)	What is embryonic stem cell? What is IPCS? Identification and uses of embryonic stem cells
3)	What is an adult stem cell? Types of adult stem cells What is a mesenchymal stem cell? What are the usage areas?
4)	Stem cell isolation and clinical applications
5)	What is a hematopoietic stem cell? Cord blood banking
6)	Characterization of mesenchymal cells by fluorescent methods
7)	General Review and Q&A
8)	Student presentations
9)	Use of stem cells in renewable therapy and tissue engineering
10)	Use of stem cells in gene therapies
11)	Production of stem cells under GMP conditions
12)	Adult Stem Cell Therapies in clinical trials settings
13)	Stem cell biomarkers in health and disease conditions
14)	Final Exam

Sources

Course Notes / Textbooks:	Kök Hücre, Alp CAN
References:	Essentials of Stem Cell Biology: Robert Lanza

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5
Program Outcomes
1) Be able to comprehend the interdisciplinary interaction with which the field is related; Ability to reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas.
2) Be able to evaluate and use new information in the field with a systematic approach.
3) Be able to examine social relations and the norms that guide these relations from a critical perspective, develop them and manage actions to change them when necessary.
4) Be able to develop new ideas and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making.
5) Be able to contribute to the process of the society in which one lives in becoming and sustaining an information society by introducing scientific, technological, social or cultural advances in the field.
6) Be able to contribute to progress in the field by independently carrying out an original study that brings innovation to the field, develops a new idea, method, design and/or application, or applies a known idea, method, design and/or application to a different field.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	Be able to comprehend the interdisciplinary interaction with which the field is related; Ability to reach original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas.	3
2)	Be able to evaluate and use new information in the field with a systematic approach.	3
3)	Be able to examine social relations and the norms that guide these relations from a critical perspective, develop them and manage actions to change them when necessary.	3
4)	Be able to develop new ideas and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making.	3
5)	Be able to contribute to the process of the society in which one lives in becoming and sustaining an information society by introducing scientific, technological, social or cultural advances in the field.	3
6)	Be able to contribute to progress in the field by independently carrying out an original study that brings innovation to the field, develops a new idea, method, design and/or application, or applies a known idea, method, design and/or application to a different field.	3

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 40
Final	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	14	10			140
Midterms	1	6	1		7
Final	1	8	1		9
Total Workload					156