Molecular Oncology (DR) Preview
PhD	TR-NQF-HE: Level 8	QF-EHEA: Third Cycle	EQF-LLL: Level 8

Course Introduction and Application Information

Course Code:

MONK6110

Course Name:

Cancer Cytogenetics

Semester:

Spring

Course Credits:

ECTS

Language of instruction:

Turkish

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Compulsory Courses

Course Level:

PhD

TR-NQF-HE:8. Master`s Degree

QF-EHEA:Third Cycle

EQF-LLL:8. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator:

Dr. Öğr. Üy. SÜREYYA BOZKURT

Course Lecturer(s):

Asst.Prof.Süreyya Bozkurt

Course Assistants:

Course Objective and Content

Course Objectives:

The aim of this course is to provide information about cancer genetics and cytogenetics and to learn its relevance to the clinic. It is also aimed to learn the roles of genetic and cytogenetic anomalies in the formation and progression of cancer. In addition, it will be learned how cytogenetic and molecular genetic information can be a guide in monitoring the prognosis of cancer patients and in their treatment.

Course Content:

To learn the effects of genetic mechanisms disrupted in cancer on the formation and development of cancer. Learning the roles of tumor suppressor and oncogenes in cancer development. Familial inheritance in cancers. To learn the clinical applications of cytogenetic and molecular cytogenetic data.

Learning Outcomes

The students who have succeeded in this course;
1) Ability to evaluate expert knowledge
2) To understand the interdisciplinary interaction
3) Current and high-level knowledge research ability in the field
4) To deepen and develop the relevant program's own knowledge in the field
5) To learn the effects of genetic mechanisms deteriorated in cancer on the formation and development of cancer.

Course Flow Plan

Week	Subject	Related Preparation
1)	Genomic instability and cancer
2)	Role of tumor suppressor genes in cancer development
3)	Role of oncogenes in cancer development
4)	Roles of DNA repair genes in cancer development
5)	Altered signal transduction pathways in cancer
6)	Cancer-causing mechanisms of DNA cancer viruses and retroviruses
7)	Familial inheritance in cancers
8)	Deregulation cell cycle and control in cancer
9)	Cancer-causing mechanisms of viruses and retroviruses
10)	Clinical applications of cancer genetics I-Clinic applications of cytogenetic data
11)	Clinical applications of cancer genetics II- Clinical applications of molecular cytogenetic data
12)	Student presentations
13)	Student Presentations
14)	Student Presentations

Sources

Course Notes / Textbooks:	Watson JD, Baker TA,Bell SB, Gann A,Lavine M, Losick R. Molecular Biology of the Gene. Alberts B, Johnson A, Lewis J, Morgan D, Raf M, Roberts K, Walter P.Molecular Biology of the Cell.
References:

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5
Program Outcomes
1) To be able to define, evaluate and use current and advanced knowledge of cancer and molecular cancer
2) To be able to research, comprehend and analyze a scientific and technological issue in the field of molecular cancer with a systematic approach.
3) Ability to develop, design, adapt and implement new and complex ideas about the molecular mechanisms of cancer at an expert level with original thinking and/or research
4) To be able to comprehend the interdisciplinary interaction with which the molecular cancer field is related, to develop a new method, design and/or application with a new idea or a known idea.
5) To gain the ability to synthesize, analyze, interpret, question and criticize information about treatment approaches developed against cancer
6) Tp develop new ideas and methods in the field by using high-level skills such as problem solving and decision making in their studies.
7) To have good communication skills in their work and being able to critically examine and develop the norms that guide these relationships, and to manage actions to change them when necessary
8) To have an awareness of ethical responsibility in their research and to be able to defend their findings by using advanced written, verbal and visual communication.
9) To contribute to the solution of social, scientific, computational and ethical problems encountered in the field of molecular cancer and to support the development of these values.
10) To be able to interpret research and study results and expand the limits of knowledge in the field by producing an original work.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	To be able to define, evaluate and use current and advanced knowledge of cancer and molecular cancer
2)	To be able to research, comprehend and analyze a scientific and technological issue in the field of molecular cancer with a systematic approach.
3)	Ability to develop, design, adapt and implement new and complex ideas about the molecular mechanisms of cancer at an expert level with original thinking and/or research
4)	To be able to comprehend the interdisciplinary interaction with which the molecular cancer field is related, to develop a new method, design and/or application with a new idea or a known idea.
5)	To gain the ability to synthesize, analyze, interpret, question and criticize information about treatment approaches developed against cancer
6)	Tp develop new ideas and methods in the field by using high-level skills such as problem solving and decision making in their studies.
7)	To have good communication skills in their work and being able to critically examine and develop the norms that guide these relationships, and to manage actions to change them when necessary
8)	To have an awareness of ethical responsibility in their research and to be able to defend their findings by using advanced written, verbal and visual communication.
9)	To contribute to the solution of social, scientific, computational and ethical problems encountered in the field of molecular cancer and to support the development of these values.
10)	To be able to interpret research and study results and expand the limits of knowledge in the field by producing an original work.

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Presentation	1	% 40
Final	1	% 60
total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	2	0	1	20	42
Laboratory	1	0	1	20	21
Presentations / Seminar	1	1	2	30	33
Homework Assignments	1	1	2	20	23
Total Workload					119