Molecular Oncology (DR) | |||||
PhD | TR-NQF-HE: Level 8 | QF-EHEA: Third Cycle | EQF-LLL: Level 8 |
Course Code: | MONK6110 | ||||
Course Name: | Cancer Cytogenetics | ||||
Semester: | Spring | ||||
Course Credits: |
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Language of instruction: | Turkish | ||||
Course Condition: | |||||
Does the Course Require Work Experience?: | No | ||||
Type of course: | Compulsory Courses | ||||
Course Level: |
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Mode of Delivery: | Face to face | ||||
Course Coordinator: | Doç. Dr. SÜREYYA BOZKURT | ||||
Course Lecturer(s): | Asst.Prof.Süreyya Bozkurt | ||||
Course Assistants: |
Course Objectives: | The aim of this course is to provide information about cancer genetics and cytogenetics and to learn its relevance to the clinic. It is also aimed to learn the roles of genetic and cytogenetic anomalies in the formation and progression of cancer. In addition, it will be learned how cytogenetic and molecular genetic information can be a guide in monitoring the prognosis of cancer patients and in their treatment. |
Course Content: | To learn the effects of genetic mechanisms disrupted in cancer on the formation and development of cancer. Learning the roles of tumor suppressor and oncogenes in cancer development. Familial inheritance in cancers. To learn the clinical applications of cytogenetic and molecular cytogenetic data. |
The students who have succeeded in this course;
1) Ability to evaluate expert knowledge 2) To understand the interdisciplinary interaction 3) Current and high-level knowledge research ability in the field 4) To deepen and develop the relevant program's own knowledge in the field 5) To learn the effects of genetic mechanisms deteriorated in cancer on the formation and development of cancer. |
Week | Subject | Related Preparation |
1) | Genomic instability and cancer | |
2) | Role of tumor suppressor genes in cancer development | |
3) | Role of oncogenes in cancer development | |
4) | Roles of DNA repair genes in cancer development | |
5) | Altered signal transduction pathways in cancer | |
6) | Cancer-causing mechanisms of DNA cancer viruses and retroviruses | |
7) | Familial inheritance in cancers | |
8) | Deregulation cell cycle and control in cancer | |
9) | Cancer-causing mechanisms of viruses and retroviruses | |
10) | Clinical applications of cancer genetics I-Clinic applications of cytogenetic data | |
11) | Clinical applications of cancer genetics II- Clinical applications of molecular cytogenetic data | |
12) | Student presentations | |
13) | Student Presentations | |
14) | Student Presentations |
Course Notes / Textbooks: | Watson JD, Baker TA,Bell SB, Gann A,Lavine M, Losick R. Molecular Biology of the Gene. Alberts B, Johnson A, Lewis J, Morgan D, Raf M, Roberts K, Walter P.Molecular Biology of the Cell. |
References: |
Course Learning Outcomes | 1 |
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Program Outcomes | ||||||||||
1) To be able to define, evaluate and use current and advanced knowledge of cancer and molecular cancer | ||||||||||
2) To be able to research, comprehend and analyze a scientific and technological issue in the field of molecular cancer with a systematic approach. | ||||||||||
3) Ability to develop, design, adapt and implement new and complex ideas about the molecular mechanisms of cancer at an expert level with original thinking and/or research | ||||||||||
4) To be able to comprehend the interdisciplinary interaction with which the molecular cancer field is related, to develop a new method, design and/or application with a new idea or a known idea. | ||||||||||
5) To gain the ability to synthesize, analyze, interpret, question and criticize information about treatment approaches developed against cancer | ||||||||||
6) Tp develop new ideas and methods in the field by using high-level skills such as problem solving and decision making in their studies. | ||||||||||
7) To have good communication skills in their work and being able to critically examine and develop the norms that guide these relationships, and to manage actions to change them when necessary | ||||||||||
8) To have an awareness of ethical responsibility in their research and to be able to defend their findings by using advanced written, verbal and visual communication. | ||||||||||
9) To contribute to the solution of social, scientific, computational and ethical problems encountered in the field of molecular cancer and to support the development of these values. | ||||||||||
10) To be able to interpret research and study results and expand the limits of knowledge in the field by producing an original work. |
No Effect | 1 Lowest | 2 Average | 3 Highest |
Program Outcomes | Level of Contribution | |
1) | To be able to define, evaluate and use current and advanced knowledge of cancer and molecular cancer | |
2) | To be able to research, comprehend and analyze a scientific and technological issue in the field of molecular cancer with a systematic approach. | |
3) | Ability to develop, design, adapt and implement new and complex ideas about the molecular mechanisms of cancer at an expert level with original thinking and/or research | |
4) | To be able to comprehend the interdisciplinary interaction with which the molecular cancer field is related, to develop a new method, design and/or application with a new idea or a known idea. | |
5) | To gain the ability to synthesize, analyze, interpret, question and criticize information about treatment approaches developed against cancer | |
6) | Tp develop new ideas and methods in the field by using high-level skills such as problem solving and decision making in their studies. | |
7) | To have good communication skills in their work and being able to critically examine and develop the norms that guide these relationships, and to manage actions to change them when necessary | |
8) | To have an awareness of ethical responsibility in their research and to be able to defend their findings by using advanced written, verbal and visual communication. | |
9) | To contribute to the solution of social, scientific, computational and ethical problems encountered in the field of molecular cancer and to support the development of these values. | |
10) | To be able to interpret research and study results and expand the limits of knowledge in the field by producing an original work. |
Semester Requirements | Number of Activities | Level of Contribution |
Presentation | 1 | % 40 |
Final | 1 | % 60 |
total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 40 | |
PERCENTAGE OF FINAL WORK | % 60 | |
total | % 100 |
Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
Course Hours | 2 | 0 | 1 | 20 | 42 | ||
Laboratory | 1 | 0 | 1 | 20 | 21 | ||
Presentations / Seminar | 1 | 1 | 2 | 30 | 33 | ||
Homework Assignments | 1 | 1 | 2 | 20 | 23 | ||
Total Workload | 119 |