| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code: | PHA415 | ||||
| Course Name: | Pharmaceutical Chemistry 3 | ||||
| Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | English | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | E-Learning | ||||
| Course Coordinator: | Dr. Öğr. Üy. ONUR ŞAHİN | ||||
| Course Lecturer(s): | Dr. Göknil Pelin COŞKUN, Dr. Onur ŞAHİN | ||||
| Course Assistants: |
| Course Objectives: | To inform about the synthesis, chemical nomenclature, mechanism of action and biotransformation of parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics, cardiovascular system drugs |
| Course Content: | Parasympathomimetics, parasympatholytics, sympathomimetics, sympatholytics, cardiovascular system drugs |
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The students who have succeeded in this course;
1) Information about design, synthesis, analysis and metabolism of pharmaceutical products 2) Recognition of basic medicine-related sciences 3) Project development and presentation on pharmaceutical teamwork, research and development |
| Week | Subject | Related Preparation |
| 1) | Teo: Introduction to Autonom nervous system Lab: Introduction to Chemical Analysis and Solubility | |
| 2) | Teo: Parasympathomimetics-I Lab: Introduction to functional group analysis | |
| 3) | Teo: Parasympathomimetics-II Lab: Application of functional group analysis (Aldehyde and Ketones) | |
| 4) | Teo: Parasympatholytics I Lab: Ester and Anhydride groups | |
| 5) | Teo: Nicotinic antagonists Lab: Application of functional group analysis (Alcohols), Drugs containing alcohol group | |
| 6) | Teo: Sympathomimetics Lab: Introduction to instrumental analysis methods | |
| 7) | Teo: Midterm Exam Lab: Midterm Exam | |
| 8) | Teo: Indirect Sympathomimetics Lab: Instrumental analysis methods (Uv-vis) Application | |
| 9) | Teo: Alpha Receptor Blocker Sympatholytics Lab: IR spectroscopy Application | |
| 10) | Teo: Beta receptors sympatholitic blockers Lab: NMR (Nuclear magnetic resonance) Spectroscopy | |
| 11) | Teo: Cardiovascular system drugs (drugs used in heart failure) Lab:NMR Spectroscopy Application | |
| 12) | Teo: Antihypertansive agents I and II Lab: Mass Spectrometer | |
| 13) | Teo: Antianginal drugs Lab: Mass spectrometry Application | |
| 14) | Teo: Antiarrhythmic drugs Lab: Unknown sample analysis |
| Course Notes / Textbooks: | 1) Foye Medisinal Kimya Temel İlkeleri, T.L.emke, S.W.Zito, V.F.Roche, D.A.Williams, Çev.Edit.Öztekin Algül, Kayhan Bolelli |
| References: | 1-Farmasötik Kimya Hacettepe Üniversitesi Yayınları ISBN: 978-975-491-171-8 3. Baskı, Aralık 2013 2-Foye's Principles of Medicinal Chemistry Publication Date: March 8, 2012 ISBN-10: 1609133455 ISBN-13: 978-1609133450 Edition: Seventh, North American Edition 3-Burger's Medicinal Chemistry, Drug Discovery and Development 7th Edition, 8 Volume Set ISBN: 978-0-470-27815-4 September 2010 4-Pharmaceutical Chemistry, David G. Watson (Author) Publication Date: February 18, 2011 ISBN-10: 0443072329 ISBN-13: 978-0443072321 Edition: 1 5-Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry Publication Date: March 2, 2010 ISBN-10: 0781779294 ISBN-13: 978-0781779296 Edition: Twelfth, North American Edition |
| Course Learning Outcomes | 1 |
2 |
3 |
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| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 3 | 3 | 3 | ||||||||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 2 | 2 | 2 | ||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 3 | 3 | 3 | ||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 1 | 1 | 1 | ||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 1 | 1 | 1 | ||||||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 3 | 3 | 3 | ||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |||||||||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 2 | 2 | 2 | ||||||||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 2 | 2 | 2 | ||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 3 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 2 |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 3 |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 1 |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 1 |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 3 |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 2 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 2 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 28 |
| Laboratory | 14 | 42 |
| Study Hours Out of Class | 14 | 28 |
| Midterms | 2 | 11 |
| Final | 2 | 21 |
| Total Workload | 130 | |