ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | ECZ417 | ||||
| Course Name: | Pharmaceutical Technology 3 | ||||
| Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | E-Learning | ||||
| Course Coordinator: | Dr. Öğr. Üy. ABDULLAH LEVENT ALPARSLAN | ||||
| Course Lecturer(s): | Prof. Dr. A. Yekta Özer | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | Learning of the fundamental preparation methods, dose calculations, radiolabelling, quality control tests of Radiopharmaceuticals. The difference is between Radiopharmaceuticals and conventional/non-radioactive drugs. Radiopharmaceuticals available in pharmacopeias for diagnosis and therapy. |
| Course Content: | Fundamentals of preparation stages and applications of radioactive drugs from radiopharmacy viewpoint. Preparation and quality control of Radiopharmaceuticals used for diagnosis and therapy in Nuclear Medicine practice. Related technical data and quality control; radiostability, Good Radiopharmacy Practice (GRP), radiation protection and usage of Radiopharmaceuticals in clinic. |
Learning Outcomes
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The students who have succeeded in this course;
1) Student knows fundamental preparation principles of Radiopharmaceuticals 2) Student knows main methods of radiation protection during 3) Student learns radiopharmaceuticals preparation/studies 4) Student knows radioactive dose/ radiopharmaceuticals dose calculations 5) Critical properties of an ideal radiopharmaceutical and decision of radiopharmaceutical use either in diagnosis or therapy. |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Introduction, history, administration and principle of Radiopharmaceuticals | |
| 2) | Ideal Radiopharmaceuticals, properties and ATC codes | |
| 3) | Radiolabelling methods | |
| 4) | Preparation methods of Radiopharmaceuticals | |
| 5) | Classification of Radiopharmaceuticals and industrial production | |
| 6) | Radiopharmaceuticals used for diagnosis and therapy | |
| 6) | Radiopharmaceuticals used for diagnosis and therapy | |
| 7) | Tc-Radiopharmaceuticals | |
| 8) | Tc-Radiopharmaceuticals | |
| 9) | I-131, I-123, I-127 Radioiodinated Radiopharmaceuticals | |
| 10) | PET (F-18 Radiolabelled) Radiopharmaceuticals | |
| 11) | Good Radiopharmacy Practice (GRP) | |
| 12) | Waste Disposal Management in Radiopharmaceuticals | |
| 13) | Presentation of assignments | |
| 14) | Presentation of assignments | |
| 15) | Final exams |
Sources
| Course Notes / Textbooks: | Fundamentals of Nuclear Pharmacy. (Gopal Saha), Springer-Verlag, New York, 1987 Textbook of Radiopharmacy. Theory and Practice. (Charles B. Sampson), Gordon and Breach Sci. Publishers, New York, Philedalphia, 1990. |
| References: | Türkiye’de Radyofarmasi Laboratuvarları İyi Radyofarmasi Uygulamaları (GRP) ve Kalite Yönetim Sistemleri (A. Yekta Özer, İ. Ethem Atak), Ankara, 2005 |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 3 | ||||||||||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 3 | ||||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 3 | ||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 3 | ||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 | ||||||||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 3 | ||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 3 | 3 | 3 | ||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 | ||||||||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 2 | 2 | 2 | 2 | 2 | ||||||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 1 | 1 | 1 | 1 | 1 | ||||||
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 3 |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 28 |
| Study Hours Out of Class | 14 | 28 |
| Midterms | 3 | 6 |
| Final | 2 | 4 |
| Total Workload | 66 | |