DENT111 Medical Biology and GeneticsIstinye UniversityDegree Programs Dentistry (English)General Information For StudentsDiploma SupplementErasmus Policy StatementNational Qualifications
Dentistry (English)

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Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code: DENT111
Course Name: Medical Biology and Genetics
Semester: Fall
Course Credits:
ECTS
4
Language of instruction: English
Course Condition:
Does the Course Require Work Experience?: No
Type of course: Compulsory Courses
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator: Dr. Öğr. Üy. ÖYKÜ GÖNÜL GEYİK
Course Lecturer(s): Prof.Dr. Veysel Sabri HANÇER Asst.Prof.Dr. Süreyya BOZKURT Asst.Prof.Dr. Öykü GÖNÜL GEYİK
Course Assistants:

Course Objective and Content

Course Objectives: The aim of this course is to teach students cell structure and functioning at molecular and genetic level.
Course Content: Learning the basic biology and genetics concepts, understanding the molecular and genetic mechanisms of the cell and evaluating the application of these concepts in the field of medicine and dentistry.

Learning Outcomes

The students who have succeeded in this course;
1) Learns the structures of cells and explains the functions of organelles.
2) Explain the properties and functions of chromosome, DNA and RNA.
3) Explain DNA replication.
4) Define mitosis and meiosis.
5) Explains the cell cycle stages and control points.
6) Discuss transcription and its control.
7) Explain the genetic code and protein synthesis.
8) Indicate the relationship between mutations and DNA repair mechanisms.
9) Explain cell death and its mechanisms.

Course Flow Plan

Week Subject Related Preparation
1) Meet & Greet, Introduction of the syllabus and curriculum, Genome Organization
2) Structural and Common Properties of Prokaryotic and Eukaryotic Cells, Cell Membrane
3) Genome Structure Overview Human Genome and Organization -
4) Nucleus Structure and Organization, General Structure and Functions of Chromosomes -
5) Structure and function of ribosome, Structure and Function of Lysosome, Structure and Function of the Endoplasmic Reticulum -
6) Structure and function of peroxisome, Structure and Function of Mitochondria, Structure and Function of the Golgi Apparatus -
7) Cytoskeleton, Cell-Cell Connections and Adhesion Molecules
8) Midterm Exam
9) Structure and properties of DNA and RNA, DNA Replication
10) Cell division: Mitosis-Meiosis, Cell cycle and its control
11) Eukaryotic transcription, Genetic Code and Translation
12) Control of Gene Expression, Cell Death
13) Mutation and Detection Methods, DNA Repair Mechanisms
14) Epigenetic Mechanisms, Intercellular Communication, Intracellular Messenger Systems

Sources

Course Notes / Textbooks: - Goodman's Medical Cell Biology, Academic Press, 2020
- Campbell Biology 10th Edition, Pearson, 2014
References: - William S. Klug, Michael R. Cummings, Concepts of Genetics, 11th edition, Pearson, 2014
- Cooper, G.M. The Cell: A Molecular Approach 8e, Oxford University Press, 2018

Course - Program Learning Outcome Relationship

Course Learning Outcomes

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9

Program Outcomes
1) Has basic and up-to-date knowledge in the field of dentistry, follows scientific publications, and applies evidence-based data to his/her professional practice. 2 2 2 2 2 2 2 2 2
2) Knows well and effectively uses devices, tools, and materials specific to diagnosis and treatment in the field of dentistry.
3) Evaluates the knowledge in the field of dentistry critically, integrates it with the knowledge of disciplines in the field of health, uses it by analyzing and synthesizing it. 2 2 2 2 2 2 2 2 2
4) Produces projects related to the field of dentistry, can work with other health disciplines, takes part as a member of the research team and evaluates and reports the results obtained at a scientific level. 2 2 2 2 2 2 2 2 2
5) Uses information that will contribute to the dentistry profession during practice, takes responsibility, and produces solutions in unforeseen situations. 2 2 2 2 2 2 2 2 2
6) Shares, compares, and exchanges dental knowledge with professional colleagues in social and scientific environments in written, verbal, and visual forms.
7) Within the framework of social, scientific, and ethical values including patient privacy, communicates with patients and their relatives, knows all the characteristics of the patient, and recommends the most appropriate treatment with a patient-centered approach.
8) Follows technological developments, participates in national and international studies, and shares and presents own observations, experiences, and research to further advance dental practices.
9) By adopting the principle of lifelong learning throughout the dentistry profession, follows current evidence-based dental knowledge and uses it during his professional practice.
10) During dental practice, in cases such as abuse and addiction, performs the treatment by exhibiting the behaviors required by social ethics and legal rules, and collects and records the relevant data.
11) Uses basic and current knowledge in the field of dentistry during professional practice for the benefit of society within the framework of national values and country realities.
12) In natural disasters and emergency cases, takes the protective measures required by the dentistry profession; performs professional practices that benefit patients and society
13) Generates ideas regarding health policy in dentistry, prioritizes individual and public health, and carries out preventive and therapeutic medical practices within the framework of scientific, ethical, and quality processes.
14) Differentiates the signs and symptoms commonly encountered in the dentistry profession, makes a treatment plan and refers when necessary, and manages diseases and clinical situations regarding their urgency and patient priority.
15) Can assume the leadership responsibility of the team he/she works for, manage it following scientific criteria, and support the professional development of the team.

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Average 3 Highest
       
Program Outcomes Level of Contribution
1) Has basic and up-to-date knowledge in the field of dentistry, follows scientific publications, and applies evidence-based data to his/her professional practice. 2
2) Knows well and effectively uses devices, tools, and materials specific to diagnosis and treatment in the field of dentistry.
3) Evaluates the knowledge in the field of dentistry critically, integrates it with the knowledge of disciplines in the field of health, uses it by analyzing and synthesizing it. 2
4) Produces projects related to the field of dentistry, can work with other health disciplines, takes part as a member of the research team and evaluates and reports the results obtained at a scientific level. 2
5) Uses information that will contribute to the dentistry profession during practice, takes responsibility, and produces solutions in unforeseen situations. 2
6) Shares, compares, and exchanges dental knowledge with professional colleagues in social and scientific environments in written, verbal, and visual forms.
7) Within the framework of social, scientific, and ethical values including patient privacy, communicates with patients and their relatives, knows all the characteristics of the patient, and recommends the most appropriate treatment with a patient-centered approach.
8) Follows technological developments, participates in national and international studies, and shares and presents own observations, experiences, and research to further advance dental practices.
9) By adopting the principle of lifelong learning throughout the dentistry profession, follows current evidence-based dental knowledge and uses it during his professional practice.
10) During dental practice, in cases such as abuse and addiction, performs the treatment by exhibiting the behaviors required by social ethics and legal rules, and collects and records the relevant data.
11) Uses basic and current knowledge in the field of dentistry during professional practice for the benefit of society within the framework of national values and country realities.
12) In natural disasters and emergency cases, takes the protective measures required by the dentistry profession; performs professional practices that benefit patients and society
13) Generates ideas regarding health policy in dentistry, prioritizes individual and public health, and carries out preventive and therapeutic medical practices within the framework of scientific, ethical, and quality processes.
14) Differentiates the signs and symptoms commonly encountered in the dentistry profession, makes a treatment plan and refers when necessary, and manages diseases and clinical situations regarding their urgency and patient priority.
15) Can assume the leadership responsibility of the team he/she works for, manage it following scientific criteria, and support the professional development of the team.

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Midterms 1 % 40
Final 1 % 60
total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
total % 100

Workload and ECTS Credit Calculation

Activities Number of Activities Preparation for the Activity Spent for the Activity Itself Completing the Activity Requirements Workload
Course Hours 28 1 2 84
Midterms 1 6 1 7
Final 1 12 1 13
Total Workload 104