| Cancer Biology and Pharmacology (Master) (with Thesis) | |||||
| Master | TR-NQF-HE: Level 7 | QF-EHEA: Second Cycle | EQF-LLL: Level 7 | ||
| Course Code: | KBY5014 | ||||
| Course Name: | Cancer Cell Metabolism | ||||
| Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Departmental Elective | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Dr. Öğr. Üy. CANER GEYİK | ||||
| Course Lecturer(s): | Caner Geyik, Huri Bulut | ||||
| Course Assistants: |
| Course Objectives: | To inform about cancer cell's energy use, anabolic pathway changes, signal pathways responsible for regulating metabolic processes and targeting cancer metabolism changes for treatment purposes. |
| Course Content: | Changes in cellular metabolism in cancer |
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The students who have succeeded in this course;
1) Recognizes the alterations in energy metabolism of cancer cells 2) Compares energy production in cancer with healthy cells 3) Compares the response to reactive oxygen species in healthy cells and cancer cells 4) Defines hypoxia and knows its relationship with cancer 5) Know the mechanisms of apoptosis 6) Knows important signaling pathways affecting cancer metabolism 7) Knows the treatment targets in cancer metabolism |
| Week | Subject | Related Preparation |
| 1) | Introduction to Cancer Cell Metabolism | |
| 2) | Energy Metabolism in Cancer I | |
| 3) | Energy Metabolism in Cancer II | |
| 4) | Biomacromolecule Synthesis in Cancer | |
| 5) | Antioxidant Defense and Cancer | |
| 6) | Hypoxia | |
| 7) | Signal Transduction Mechanisms | |
| 8) | MIDTERM | |
| 9) | PI3K-AKT- mTOR Pathway | |
| 10) | Ras Pathway | |
| 11) | Myc Pathway | |
| 12) | Apoptosis | |
| 13) | Therapy Targets in Cancer Metabolism I | |
| 14) | Therapy Targets in Cancer Metabolism II | |
| 15) | Final | |
| 16) | Final |
| Course Notes / Textbooks: | |
| References: |
| Course Learning Outcomes | 1 |
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7 |
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| Program Outcomes | ||||||||
| 1) The ability to define basic concepts of Cancer Biology and Pharmacology, get information objectively about the related field within the scope of the program | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |
| 2) Having knowledge about the molecular mechanisms of cancer, learning the process of carcinogenesis at molecular level | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
| 3) Learning of pharmacology and anti-cancer drug development, screening and relevant molecular/cellular techniques (cytotoxicity, etc.), get information about the postgraduate regulation related to cancer research and drug development, cooperation and experience share with institutions providing technological support | ||||||||
| 4) The ability to synthesize, analyze, interpret, interrogate and criticize the relevant information on cancer biology and drug development | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |
| 5) The ability to use good communication skills and computer technology efficiently in their work | ||||||||
| 6) The ability to convey/present the findings of the research and the results either verbally or in writing | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
| 7) The ability to carry out professional and academic studies independently using accumulated knowledge and to work and take responsibility as a team member with other professions working in this field | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| 8) Having a sense of ethical responsibility in research | ||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | The ability to define basic concepts of Cancer Biology and Pharmacology, get information objectively about the related field within the scope of the program | 3 |
| 2) | Having knowledge about the molecular mechanisms of cancer, learning the process of carcinogenesis at molecular level | 2 |
| 3) | Learning of pharmacology and anti-cancer drug development, screening and relevant molecular/cellular techniques (cytotoxicity, etc.), get information about the postgraduate regulation related to cancer research and drug development, cooperation and experience share with institutions providing technological support | |
| 4) | The ability to synthesize, analyze, interpret, interrogate and criticize the relevant information on cancer biology and drug development | 3 |
| 5) | The ability to use good communication skills and computer technology efficiently in their work | |
| 6) | The ability to convey/present the findings of the research and the results either verbally or in writing | 2 |
| 7) | The ability to carry out professional and academic studies independently using accumulated knowledge and to work and take responsibility as a team member with other professions working in this field | 1 |
| 8) | Having a sense of ethical responsibility in research |
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 40 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 28 |
| Study Hours Out of Class | 16 | 48 |
| Midterms | 1 | 2 |
| Final | 16 | 38 |
| Total Workload | 116 | |