Medicine (English) Preview
Bachelor	TR-NQF-HE: Level 7	QF-EHEA: Second Cycle	EQF-LLL: Level 7

Course Introduction and Application Information

Course Code:

MED031

Course Name:

Animal Models for The Study of Human Disease

Semester:

Fall

Course Credits:

ECTS

Language of instruction:

English

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

Bachelor

TR-NQF-HE:7. Master`s Degree

QF-EHEA:Second Cycle

EQF-LLL:7. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator:

Dr. Öğr. Üy. İLKNUR DURSUN

Course Lecturer(s):

Assist. Prof. Dr. İlknur Dursun

Course Assistants:

Course Objective and Content

Course Objectives:

In this course, students will learn the basic process of designing research and testing using animals as models. During this course, the students will gain information about how experimental models can contribute to curing human diseases. We will discuss how different experimental models ranging from unicellular organisms to invertebrates and vertebrates animals have contributed to our growing understanding of the molecular basis of human diseases such as diseases of the nervous system, cancer and diabetes.

Course Content:

The basic concepts in medical research and cover the general principles of the ethical care and use of animals in research, training, and testing.

Learning Outcomes

The students who have succeeded in this course;
1) Students will have ability and skills in understanding issues in medical research.
2) Students will learn how to apply research findings from different fields to the medical practice and research.
3) Students will gain basic principles and skills about the process of reading, interpreting and preparing a scientific article, thesis proposal and report.
4) Students will experience asking questions and participating in a seminar discussion.
5) Students will learn about research methods and experimental animal research from various medical disciplines.

Course Flow Plan

Week	Subject	Related Preparation
1)	Introduction to the course content
2)	Introduction to animal research in medicine / A Brief History of Animal Modeling
3)	Student Seminar Use of rodents as models of human diseases / Use of primates as models of human diseases
4)	Student Seminar: Invertebrate Animals Used for Experimental Purposes / Vertebrate Animals Used for Experimental Purposes
5)	Student Seminar: Animal models of Schizophrenia / Animal Models of Mood Disorders: Focus on Bipolar Disorder and Depression
6)	Student Seminar: Animal Models of Alzheimer Disease / Animal models of Parkinson's disease
7)	Student Seminar: The use of animal models in diabetes research / Animal Models of Metabolic Syndrome
8)	Student Seminar: Animal Models in Cardiovascular Research / Animal Models for Studying Prevention and Treatment of Cancer
9)	Student Seminar: Genetically Modified Animal Models / Animal Models for the Study of Human Genetic Disease
10)	Student Seminar: Animal Models in Nutrition and Obesity Research / Animal Models for the Study of Neonatal Disease
11)	Student Seminar: Animal Models for Studying Prevention and Treatment of Cancer / Animal Models of Human Viral Diseases
12)	Student Seminar: Animal models in addiction and Animal Models of Drug Abuse / Animal Models for the Study of Human Neurodegenerative Diseases
13)	Student Seminar: Animal models in toxicological studies / Animal Models of Eye Diseases
14)	Seminar: Surgical techniques in animals research / Cosmetic testing on animals

Sources

Course Notes / Textbooks:	Animal Models for the Study of Human Disease Editors: P. Michael Conn eBook ISBN: 9780124159129 -Updated Research Papers
References:	Animal Models for the Study of Human Disease Editors: P. Michael Conn eBook ISBN: 9780124159129 -Updated Research Papers

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5
Program Outcomes
1) When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.	2	2	2	2	2
2) knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.	3	3	3	3	3
3) is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.	1	1	1	1	1
4) knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.	3	3	3	3	3
5) can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.	2	2	2	2	2
6) knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7) can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8) knows the clinical decision-making process, evidencebased medicine practices and current approaches.
9) knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10) knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11) is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12) knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.	3	3	3	3	3
13) can collect health data, analyze them, present them in summary, and prepare forensic reports.	3	3	3	3	3
14) knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.	3	3	3	3	3
15) knows employee health, environment and occupational safety issues and takes responsibility when necessary.	2	2	2	2	2
16) knows health policies and is able to evaluate their effects in the field of application.	1	1	1	1	1
17) keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.	3	3	3	3	3
18) Applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.	3	3	3	3	3

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	When Istinye University Faculty of Medicine student is graduated who knows the historical development of medicine, medical practices, and the medical profession and their importance for society.	2
2)	knows the normal structure and function of the human body at the level of molecules, cells, tissues, organs and systems.	3
3)	is capable of systematically taking an accurate and effective social and medical history from their patients and make a comprehensive physical examination.	1
4)	knows the laboratory procedures related to diseases; In primary care, the necessary material (blood, urine, etc.) can be obtained from the patient with appropriate methods and can perform the necessary laboratory procedures for diagnosis and follow-up or request laboratory tests.	3
5)	can distinguish pathological changes in structure and functions during diseases from physiological changes and can Interpret the patient's history, physical examination, laboratory and imaging findings, and arrive at a pre-diagnosis and diagnosis of the patient's problem.	2
6)	knows, plans and applies primary care and emergency medical treatment practices, rehabilitation stages.
7)	can keep patient records accurately and efficiently, know the importance of confidentiality of patient information and records, and protects this privacy.
8)	knows the clinical decision-making process, evidencebased medicine practices and current approaches.
9)	knows and applies the basic principles of preventive health measures and the protection of individuals from diseases and improving health, and recognizes the individual and/or society at risk, undertakes the responsibility of the physician in public health problems such as epidemics and pandemics.
10)	knows the biopsychosocial approach, evaluates the causes of diseases by considering the individual and his / her environment.
11)	is capable of having effective oral and/or written communication with patients and their relatives, society and colleagues.
12)	knows the techniques, methods and rules of researching. It contributes to the creation, sharing, implementation and development of new professional knowledge and practices by using science and scientific method within the framework of ethical rules.	3
13)	can collect health data, analyze them, present them in summary, and prepare forensic reports.	3
14)	knows the place of physicians as an educator, administrator and researcher in delivery of health care. It takes responsibility for the professional and personal development of own and colleagues in all interdisciplinary teams established to increase the health level of the society.	3
15)	knows employee health, environment and occupational safety issues and takes responsibility when necessary.	2
16)	knows health policies and is able to evaluate their effects in the field of application.	1
17)	keeps medical knowledge up-to-date within the framework of lifelong learning responsibility.	3
18)	Applies own profession by knowing about ethical obligations and legal responsibilities, prioritizing human values and with self-sacrifice throughout own medical life.	3

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Attendance	14	% 10
Presentation	3	% 60
Final	1	% 30
total		% 100
PERCENTAGE OF SEMESTER WORK		% 70
PERCENTAGE OF FINAL WORK		% 30
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	14	0	2		28
Presentations / Seminar	3	6	1		21
Final	1	5	1		6
Total Workload					55