Pharmacy (English) Preview
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code:

PHA040

Course Name:

Microbiota Probiotics Prebiotics Synbiotics

Semester:

Fall

Course Credits:

ECTS

Language of instruction:

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator:

Dr. Öğr. Üy. BETÜL GİRAY

Course Lecturer(s):

Dr. Öğr. Üye. Betül GİRAY

Course Assistants:

Course Objective and Content

Course Objectives:

The aim of this course is to give detailed information about microbiota, prebiotics and probiotics, to convey the relationship between microbiota and diseases, to comprehend the effects of nutrition, prebiotics, probiotics and synbiotics on microbiota, to observe the differences between the microbiota of healthy individuals and diseased individuals, and to comprehend the importance of a healthy microbiota.

Course Content:

This course includes microbiota and history, relationships between microbiota and diseases, human anatomical regions and classification of microorganisms, effects of nutrition on microbiota, effects of antibiotic use and other chemotherapeutic drugs on intestinal microbiota, probiotics, prebiotics and synbiotics. It also provides comprehensive information on the positive effects of probiotics, prebiotics and synbiotics on microbiota.

Learning Outcomes

The students who have succeeded in this course;
1) Will be able to define microbiota, interpret the relationship between human microbiota and health.
2) will be able to classify the effects of antibiotics and chemotherapeutic on microbiota.
3) Will be able to classify microorganisms in relation with human anatomical regions.
4) Will be able to define the relationships between microbiota and diseases.
5) Will be able to distinguish the differences between the microbiota of healthy individuals and the microbiota of individuals with diseases.
6) Will be able to describe the effects of probiotics, prebiotics and synbiotics on microbiota.
7) They will be able to develop their article research and presentation skills.

Course Flow Plan

Week	Subject	Related Preparation
1)	Importance and History of Microbiota	Lesson Notes
2)	Article review and presentation on the microbiota of healthy individuals and the microbiota of diseased individuals	Open access research papers
3)	Anatomical regions and their microbial flora contents
4)	Gastrointestinal System Microbiota and Its Relationship with Diseases	Lesson Notes
5)	Article review and presentation on microbiota and autoimmune diseases	Open access research papers
6)	Article review and presentation on the relationship between microbiota and cancer	Open access research papers
7)	Microbiota and diabetes-related article review and presentation	Open access research papers
8)	Midterm Exam	All presantations, lesson notes and research papers.
9)	Probiotics, prebiotics and synbiotics	Lesson Notes
10)	Will be able to describe the effects of probiotics, prebiotics and synbiotics on microbiota and human health.	Lesson Notes
11)	Article review and presentation on probiotics	Open access research papers
12)	Article review and presentation on prebiotics	Open access research papers
13)	Article review and presentation on synbiotics	Open access research papers
14)	Current approaches in the field of microbiota: Fecal transplantation	Lesson Notes
15)	Final Exam	All presentations, lesson notes and research papers

Sources

Course Notes / Textbooks:	Microbiota: Current Research and Emerging Trends, Takashi Matsumoto (Editor) and Yoshio Yamaoka (Editor), 2018, Open Access Paper, Açık Erişim Paper
References:	Ders Sunumları, makaleler, Lesson notes and open access papers.

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5	6	7
Program Outcomes
1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules.
2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently.
3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms.	2	2	2	2	2	2	2
4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods.
5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes.
6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy.
7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates.
8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products.
9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them.
10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values.
11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers.	2	2	2	2	2	2	2

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules.
2)	Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently.
3)	Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms.	2
4)	Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods.
5)	Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes.
6)	Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy.
7)	Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates.
8)	He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products.
9)	Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them.
10)	As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values.
11)	He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers.	2

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Midterms	1	% 30
Final	1	% 70
total		% 100
PERCENTAGE OF SEMESTER WORK		% 30
PERCENTAGE OF FINAL WORK		% 70
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Workload
Course Hours	14	28
Study Hours Out of Class	14	54
Midterms	1	2
Final	1	2
Total Workload		86