ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | ECZ019 | ||||
| Course Name: | Artificial Intelligence in Pharmacy | ||||
| Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | |||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | Yes | ||||
| Type of course: | Departmental Elective | ||||
| Course Level: |
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| Mode of Delivery: | E-Learning | ||||
| Course Coordinator: | Öğr. Gör. AYŞEGÜL ÇALIŞKAN İŞCAN | ||||
| Course Lecturer(s): | Dr. Ayşegül Çalışkan İşcan | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | We know that the pharmaceutical profession is now undeniably inseparable from the technologies of the future, which will provide the faculty and students who have the potential for high human intelligence of ISU and who have taken the research to their primary task. Pharmacy is an effective profession in all areas of the pharmaceutical industry. Since the journey of drug molecules in body components will vary according to people's genetic profiles, only pharmacist candidates will know that different genetic profiles with the same disease interact with mutated proteins, allowing the molecular structure to become a person's property. Therefore, in the stages of developing their own abilities, pharmacy students will be trained to know the technological developments very well as multidisciplinary and to create benefit models and organize the system for the health of the public. Researchers at the FACULTY of Pharmacy at ISU will understand, for example, that they have the capacity to use "Artificial Intelligence" tools to develop new cancer drugs, examine toxicological profiles and address the health challenges of not only Turkey but also countries around the world in health issues concerning drug molecules. Because artificial intelligence involves a much more advanced concentration and shaping the future than a way of thinking. People who have the use of this technology in the field of pharmacy will be ready to answer major problems in the understanding of changing the health of societies and improving them with drug molecules. Therefore, the aim of the course is to ensure that the pharmacy profession does not lag behind technological developments. |
| Course Content: | Artificial intelligence (AI) has nowadays become an important application area of the high-tech expansion of the future today. When it comes to field work rate in health, we understand that the most prominent part of this is the striking series of approaches that largely cover drug molecules and affect all pharmaceutical sectors in open-ended development. This course includes the definition of artificial intelligence, its historical process, in which areas it is used today, how it can be integrated into drug discovery and development processes, artificial intelligence-based applications in the pharmaceutical industry, artificial intelligence applications in bioinformatics and personalized medicine. |
Learning Outcomes
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The students who have succeeded in this course;
1) Have knowledge about artificial intelligence and its subgroups 2) Gains knowledge about applications and initiatives based on artificial intelligence in our country and in the world. 3) Learns the concept of pharmacogenetics 4) Have detailed information about OMIC technologies (genomics, transcriptomics, proteomics) 5) Learns how to integrate OMIC technologies into drug discovery and development processes 6) Have basic knowledge of transcriptome data and can make drug repositioning over transcriptome data. 7) Learns web tools used for drug repositioning 8) Gains knowledge about molecular docking |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Course overview - Introduction to Artificial Intelligence | |
| 2) | Artificial intelligence definition and history, Usage areas, Examples of artificial intelligence-based entrepreneurship in pharmacy | |
| 3) | Artificial Intelligence in Drug Discovery and Development Process, Pharmacogenetics | |
| 4) | OMICs Technologies | |
| 5) | Examination of genomics-drug resistance-personalized medicine relationships, Factorial effects of the roles of the proteins encoded by the genetic profile in various diseases on drug molecule formation. | |
| 6) | Transcriptome Data analysis I | |
| 7) | Transcriptome Data analysis II | |
| 8) | Midterm Week | |
| 9) | Drug repositioning, Web tools in drug repositioning | |
| 10) | Molecular docking | |
| 11) | Molecular Pathway Analyses | |
| 12) | Student Project Presentations | |
| 13) | Student Project Presentations | |
| 14) | Student Project Presentations |
Sources
| Course Notes / Textbooks: | Ders notları |
| References: | 1. Dijital Sağlık Uygulamalarında Yapay Zeka Selma Büyükgöze, Ebru Dereli, Kırklareli Üniversitesi Teknik Bilimler MYO, Kırklareli, Türkiye |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
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| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 1 | 1 | 1 | 1 | 1 | 1 | |||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |||
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 1 |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 1 |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 2 |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 1 |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 1 |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 3 |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 1 |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 1 |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 28 |
| Study Hours Out of Class | 14 | 28 |
| Midterms | 2 | 11 |
| Final | 2 | 16 |
| Total Workload | 83 | |