| Cancer Biology and Pharmacology (Master) (with Thesis) | |||||
| Master | TR-NQF-HE: Level 7 | QF-EHEA: Second Cycle | EQF-LLL: Level 7 | ||
| Course Code: | KBY5009 | ||||
| Course Name: | Molecular Toxicology | ||||
| Semester: | Fall | ||||
| Course Credits: |
|
||||
| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Departmental Elective | ||||
| Course Level: |
|
||||
| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Dr. Öğr. Üy. CANER GEYİK | ||||
| Course Lecturer(s): | Caner Geyik | ||||
| Course Assistants: |
| Course Objectives: | It aims to inform the enrolled students about the molecules that cause toxicity, their biotransformation, and the methods used to determine the toxicity of a molecule. |
| Course Content: | Cellular mechanisms of toxicology and toxicity determination methods |
|
The students who have succeeded in this course;
1) Define toxicity 2) Identify the methods that can detect cytotoxicity 3) Explain genotoxicity and genotoxicity determination methods 4) Explain biotransformation reactions 5) Recognize the mechanisms of membrane drug transport 6) Present an in vitro toxicity determination method |
| Week | Subject | Related Preparation |
| 1) | Introduction to Toxicology and General Concepts | |
| 2) | Cytotoxicity | |
| 3) | Viability and Proliferation / Article Discussion | |
| 4) | Genotoxicity I | |
| 5) | Genotoxicity II | |
| 6) | Short Quiz / Article Discussion | |
| 7) | Metal Toxicity | |
| 8) | Presentation Week I | |
| 9) | Presentation Week II | |
| 10) | Presentation Week III | |
| 11) | Biotransformation | |
| 12) | Xenobiotic Transport | |
| 13) | Toxicogenomics | |
| 14) | Toxicoproteomics |
| Course Notes / Textbooks: | |
| References: |
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
6 |
||
|---|---|---|---|---|---|---|---|---|
| Program Outcomes | ||||||||
| 1) The ability to define basic concepts of Cancer Biology and Pharmacology, get information objectively about the related field within the scope of the program | 3 | 3 | 3 | 3 | 3 | 3 | ||
| 2) Having knowledge about the molecular mechanisms of cancer, learning the process of carcinogenesis at molecular level | 1 | 1 | 1 | 1 | 1 | 1 | ||
| 3) Learning of pharmacology and anti-cancer drug development, screening and relevant molecular/cellular techniques (cytotoxicity, etc.), get information about the postgraduate regulation related to cancer research and drug development, cooperation and experience share with institutions providing technological support | 2 | 2 | 2 | 2 | 2 | 2 | ||
| 4) The ability to synthesize, analyze, interpret, interrogate and criticize the relevant information on cancer biology and drug development | ||||||||
| 5) The ability to use good communication skills and computer technology efficiently in their work | ||||||||
| 6) The ability to convey/present the findings of the research and the results either verbally or in writing | 3 | 3 | 3 | 3 | 3 | 3 | ||
| 7) The ability to carry out professional and academic studies independently using accumulated knowledge and to work and take responsibility as a team member with other professions working in this field | ||||||||
| 8) Having a sense of ethical responsibility in research | 1 | 1 | 1 | 1 | 1 | 1 | ||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | The ability to define basic concepts of Cancer Biology and Pharmacology, get information objectively about the related field within the scope of the program | 3 |
| 2) | Having knowledge about the molecular mechanisms of cancer, learning the process of carcinogenesis at molecular level | 1 |
| 3) | Learning of pharmacology and anti-cancer drug development, screening and relevant molecular/cellular techniques (cytotoxicity, etc.), get information about the postgraduate regulation related to cancer research and drug development, cooperation and experience share with institutions providing technological support | 2 |
| 4) | The ability to synthesize, analyze, interpret, interrogate and criticize the relevant information on cancer biology and drug development | |
| 5) | The ability to use good communication skills and computer technology efficiently in their work | |
| 6) | The ability to convey/present the findings of the research and the results either verbally or in writing | 3 |
| 7) | The ability to carry out professional and academic studies independently using accumulated knowledge and to work and take responsibility as a team member with other professions working in this field | |
| 8) | Having a sense of ethical responsibility in research | 1 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Quizzes | 1 | % 20 |
| Homework Assignments | 1 | % 50 |
| Presentation | 1 | % 30 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 100 | |
| PERCENTAGE OF FINAL WORK | % | |
| total | % 100 | |
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 24.5 |
| Study Hours Out of Class | 16 | 77 |
| Presentations / Seminar | 3 | 3 |
| Homework Assignments | 2 | 8 |
| Quizzes | 1 | 0.5 |
| Total Workload | 113 | |