ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | PHA306 | ||||
| Course Name: | Pharmaceutical Technology 2 | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | English | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Dr. Öğr. Üy. ABDULLAH LEVENT ALPARSLAN | ||||
| Course Lecturer(s): | Pharm. Dr. Abdullah Levent Alparslan, Pharm. Dr. Ece Özcan Bülbül | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | Examination of basic pharmaceutical preparation methods. To be able to make dose calculations according to the prescription. Comparison of single-phase and dual-phase systems with powder and tablet forms. Development of modified and controlled systems. Investigation of quality control parameters during and after formulation studies. Using resources such as pharmacopoeia in the preparation of pharmaceutical forms. Investigation of polymers used in drugs. Investigation of the effect of rheology on formulations. Investigation of new drug delivery systems. Study of traditional herbal medicine. Examination of production conditions and the importance of pilot scale evaluation. Drug stability, shelf life and calculations. An understanding of the philosophy of good manufacturing practices |
| Course Content: | Information about sterilization of drugs and contamination assessment criteria. Information about isotonic and parenteral solutions, preparation methods. Information about eye drugs, preparation methods, applications and contents of lens solutions. Information about nose and ear medications, their preparation and application. Tablets and tablet types, their preparation and controls on tablets. Polymers used in drug formulations. Information about soft and hard gelatin capsules and preparation methods. Examination of controlled release systems and novel drug delivery systems and their preparation techniques. Information about aerosols and application methods. Information on traditional herbal medicines. Investigation of drug polymers in formulation. The importance and examination of rheology in drug formulations. Drug stability studies and shelf-life calculations. Making and importance of transition studies from laboratory scale to pilot scale production. Good Manufacturing Practices philosophy and integration into production. |
Learning Outcomes
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The students who have succeeded in this course;
1) Student knows pharmaceutical basic preparation methods. 2) Student has criteria for evaluating the substances that will be included in the formulation content. Examines and calculates the shelf life of products. 3) Student knows the preparation methods of single-phase and double-phase systems. 4) Student can work with powders. Knows sterilization and contamination. 5) Student can prepare eye, nose and ear medications. 6) Student can prepare tablets, capsules and make their controls. 7) Student has knowledge about traditional herbal products. 7) Student classifies and distinguishes the flow properties of fluids 8) Student knows polymers used in drugs. 8) Student has knowledge about the production conditions and processes of drugs. |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Contamination, Sterilization and Sterile Medicines | |
| 2) | Isotonic Solutions and Parenteral Solutions | |
| 3) | Ophthalmic drugs and lens solutions | |
| 4) | Nasal Medicines | |
| 5) | Otic Drugs | |
| 6) | Tablets | |
| 7) | Coated Tablets | |
| 8) | Polymers | |
| 9) | Hard and Soft Capsules | |
| 10) | Controlled release systems and new drug delivery systems | |
| 11) | Aerosol systems | |
| 12) | Traditional herbal medicines and medical devices | |
| 13) | Rheology, incompatibility | |
| 14) | Stability, pilot scale and good manufacturing practices | |
| 15) | Final Exams |
Sources
| Course Notes / Textbooks: | EGE ÜNİVERSİTESİ FARMASÖTİK TEKNOLOJİ YAYINLARI, GAZİ ÜNİVERSİTESİ MODERN FARMASÖTİK TEKNOLOJİ EGE UNIVERSITY PHARMACEUTICAL TECHNOLOGY PUBLICATIONS, GAZI UNIVERSITY MODERN PHARMACEUTICAL TECHNOLOGY |
| References: | ANSEL’S PHARMACEUTİCAL DOSAGE FORMS AND DRUG DELİVERY SYSTEM. ED., ALLEN, POPOVİCH AND ANSEL (2005). PUBLİSHER: LİPPİNCOTT, ENCYCLOPEDİA OF PHARMACEUTİCAL TECHNOLOGY, INFORMA HEALTHCARE, NEW YORK (2007). |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
6 |
7 |
7 |
8 |
8 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 3 | ||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 2 | ||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 3 | ||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | |||||||||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 1 | ||||||||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 3 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 3 |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 2 |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 28 |
| Laboratory | 14 | 42 |
| Study Hours Out of Class | 14 | 28 |
| Midterms | 3 | 14 |
| Final | 3 | 28 |
| Total Workload | 140 | |