ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | PHA304 | ||||
| Course Name: | Pharmacology 2 | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | English | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Prof. Dr. MEHMET FERİT İSBİR | ||||
| Course Lecturer(s): | Prof. Dr. Mehmet F. İsbir, Assist. Prof. Dr. Oğuzhan Aydemir | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | The aim of this course is to give information about drugs affecting movement disorders and other neurodegenerative disorders; Alzheimer disease, parkinsonism and drug treatments, pain pathways, analgesics and anesthetics, CNS skeletal muscle relaxants, opioids, NSAIDs, sumatriptans, autacoids, general principles of cardiovascular system pharmacology, drugs used in the treatment of asthma, COPD |
| Course Content: | Drugs affecting movement disordes and neurodegenerative disorders ; Pharmacological treatment of Parkinson’s disesase Pharmacological treatment of Alzheimer’s disesase CNS skeletal muscle relaxants Pain General Anesthetics Local Anesthetics Analgesics, Opioids NSAIDs Sumatriptans Autacoids Indtroduction to cardiovascular system pharmacology Hypercholesterolemia and pharmacologic treatment Hypertension Treatment Peripheral vasodilators Renal Diseases and treatment Diuretics Antianginal drugs Antithrombotic drugs Heart Failure,pharmacological treatment Cardiac arrhythmias, pharmacological treatment drugs used in the treatment of asthma, COPD |
Learning Outcomes
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The students who have succeeded in this course;
1) At the end of this course, The students will learn and understand • Drugs affecting movement disorders and other neurodegenerative disorders; Alzheimer disease, parkinsonism and drug treatments, CNS skeletal muscle relaxants • pain pathways, analgesics and anesthetics Students have the understanding of/ explain the classification, mechanism of action, pharmacodynamics, pharmacokinetics, drug interactions and side effects of drugs 2) The students will learn at the end of this course • Introduction to physiology/pathophysiology of cardiovascular system and drugs used to affect the cardiovascular system , general principles of cardiovascular pharmacology •will have the understanding of drugs used to affect the cardiovascular system and can define and give examples of mchanism of action, their pharmacodynamics/pharmacokinetics, advers effects, drug interactions 3) The students will learn at the end of this course autacoids and their importance in physiological and pathophysiological conditions, pharmacologic effects of autacoids (agonists-antagonists) 4) The students will learn at the end of this course • drugs used in the treatment of respiratory disorders (asthma, COPD), define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Drugs affecting movement disordes and neurodegenerative disorders ; Pharmacological treatment of Parkinson’s disesase | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 2) | Pharmacological treatment of Alzheimer’s disesase | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 3) | CNS skeletal muscle relaxants Pain General Anesthetics | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 4) | Local Anesthetics Analgesics, Opioids | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 5) | NSAIDs Sumatriptans | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 6) | Autacoids | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 7) | Autacoids-2 Introduction to cardiovascular system pharmacology (Midterm Exam) | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 8) | Peripheral vasodilators Hypercholesterolemia and pharmacologic treatment | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 9) | Antihypertensives | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 10) | Renal Diseases and treatments Diuretics | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 11) | Antianginal drugs Antithrombotic drugs | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 12) | Heart Failure,pharmacological treatment | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 13) | Cardiac arrhythmias, pharmacological treatment | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 14) | Drugs used in the treatment of asthma and COPD | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
Sources
| Course Notes / Textbooks: | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| References: | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2007) Netter’in Resimli Farmakolojisi, Mehmet İsbir (çeviren) Nobel Tıp Kitabevleri Whalen, K., Feild, C.(yard.ed.), Radhakrishnan R.(yard.ed.) (2020) Lippincott Görsel Anlatımlı Çalışma Kitapları, Ulugöl, A. Karadağ, Ç.H., Dökmeci, D. (çeviri ed.) Nobel Tıp kitabevleri Katzung,B.G., Masters,S.B.,Trevor,A.J. (2016) Temel ve Klinik Farmakoloji, Akkan G ve ark (çev ed.) Nobel Tıp Kitabevleri Kayaalp O.S. (ed) (2018). Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Pelikan Yayıncılık Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 | 2 | 2 | 2 | |||||||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |||||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 1 | 1 | 1 | 1 | |||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 | 3 | 3 | 3 | |||||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 | 3 | 3 | 3 | |||||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 | 3 | 3 | 3 | |||||||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 | 3 | 3 | 3 | |||||||
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 3 |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 1 |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 56 |
| Study Hours Out of Class | 14 | 40 |
| Midterms | 1 | 2 |
| Final | 1 | 2 |
| Total Workload | 100 | |