Molecular Biology and Genetics (English) Preview
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code:

MBG003

Course Name:

Cancer Biology

Semester:

Fall
Spring

Course Credits:

ECTS

Language of instruction:

English

Course Condition:

Does the Course Require Work Experience?:

Type of course:

Departmental Elective

Course Level:

Bachelor

TR-NQF-HE:6. Master`s Degree

QF-EHEA:First Cycle

EQF-LLL:6. Master`s Degree

Mode of Delivery:

Face to face

Course Coordinator:

Araş. Gör. KAAN ADACAN

Course Lecturer(s):

Course Assistants:

Course Objective and Content

Course Objectives:	To give general information about definition, development and progression of cancer. To have knowledge about the basic structure and organization of the cancer cell as well as how biological events occur in a cancer cell. To inform the students about the roles of oncogenes and tumor suppressor genes, signaling pathways, metastasis, angiogenesis and cancer treatment strategies.
Course Content:	Carcinogenesis, oncogenes and tumor suppressor genes, signaling pathways, metastasis, angiogenesis, cancer stem cells, statistics, risk factors, genetic changes and biomarkers of specific cancer types, current treatment options and approaches

Learning Outcomes

The students who have succeeded in this course;
1) To be able to describe carcinogenesis
2) To be able to explain the basic structure and differences of cancer cells and healthy cells
3) To be able to explain common cancers at molecular level
4) To be able to discuss treatment approaches
5) To be able to describe the methodology used in cancer research, analyze and solve problems
6) To be able to establish the relationships between cancer cell biology and different sciences (biochemistry, genetic etc.)
7) To be able to recognize the importance of interdisciplinary and multidisciplinary studies
8) To be able to follow current developments in cell biology

Course Flow Plan

Week	Subject	Related Preparation
1)	Definition of carcinogenesis and basic concepts
2)	Oncogenes and Tumor suppressor genes
3)	Cancer signaling pathways I
4)	Cancer signaling pathways II
5)	Metastasis
6)	Angiogenesis
7)	Cancer stem cells
8)	Cancer metabolism
9)	Tumor microenvironment
10)	Cell death modes and cancer I
11)	Cell death modes and cancer II
12)	Cell death modes and cancer III
13)	Mechanism of actions of chemotherapeutics
14)	Current approaches in cancer treatment & general overview

Sources

Course Notes / Textbooks:	Kanser Moleküler Biyolojisi (Ed. Yusuf Baran), Kısayol yayıncılık Basic science of cancer (Ed. Gary D. Kruh, Kenneth D. Tew), Current Medicine Inc.
References:	Ders Notları

Course - Program Learning Outcome Relationship

Course Learning Outcomes	1	2	3	4	5	6	7	8
Program Outcomes
1) Has a theoretical and practical background in biology, chemistry, physics and mathematics, which constitute the basic knowledge in the field of molecular biology and genetics.
2) Can explain biological phenomena and events at molecular level and relate them to other basic sciences and engineering applications.
3) Has the basic laboratory knowledge and skills required by the field.
4) Works in accordance with scientific principles and ethical rules.
5) Uses procedural and mathematical software programs required for the analysis and basic evaluation of biological data at least at the European Computer License Basic Level.
6) Has the knowledge, culture and skills to follow the literature and current methods related to his field.
7) Will be able to identify the main problem in line with the needs in health, agriculture, animal husbandry, environment, industry and similar issues and offer the necessary solutions by using up-to-date technology.
8) Has the knowledge and ability to evaluate biological phenomena and events at the level of systems from an evolutionary point of view.
9) Has the ability to be involved in individual and group work, to prepare and carry out projects on specific topics, and to make written and oral presentations.
10) Uses at least one foreign language in reading, writing and speaking at B1 General Level in terms of European Language Portfolio criteria.
11) Has the ability to identify social and global problems using his / her field knowledge and to be a part of the solution in interdisciplinary cooperation.
12) Respects social, cultural and individual differences, universal values and human rights in his / her scientific and professional activities.

Course - Learning Outcome Relationship

No Effect	1 Lowest	2 Average	3 Highest

	Program Outcomes	Level of Contribution
1)	Has a theoretical and practical background in biology, chemistry, physics and mathematics, which constitute the basic knowledge in the field of molecular biology and genetics.
2)	Can explain biological phenomena and events at molecular level and relate them to other basic sciences and engineering applications.
3)	Has the basic laboratory knowledge and skills required by the field.
4)	Works in accordance with scientific principles and ethical rules.
5)	Uses procedural and mathematical software programs required for the analysis and basic evaluation of biological data at least at the European Computer License Basic Level.
6)	Has the knowledge, culture and skills to follow the literature and current methods related to his field.
7)	Will be able to identify the main problem in line with the needs in health, agriculture, animal husbandry, environment, industry and similar issues and offer the necessary solutions by using up-to-date technology.
8)	Has the knowledge and ability to evaluate biological phenomena and events at the level of systems from an evolutionary point of view.
9)	Has the ability to be involved in individual and group work, to prepare and carry out projects on specific topics, and to make written and oral presentations.
10)	Uses at least one foreign language in reading, writing and speaking at B1 General Level in terms of European Language Portfolio criteria.
11)	Has the ability to identify social and global problems using his / her field knowledge and to be a part of the solution in interdisciplinary cooperation.
12)	Respects social, cultural and individual differences, universal values and human rights in his / her scientific and professional activities.

Assessment & Grading

Semester Requirements	Number of Activities	Level of Contribution
Attendance	14	% 0
Presentation	1	% 20
Midterms	1	% 30
Final	1	% 50
total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
total		% 100

Workload and ECTS Credit Calculation

Activities	Number of Activities	Preparation for the Activity	Spent for the Activity Itself	Completing the Activity Requirements	Workload
Course Hours	14	0	3		42
Study Hours Out of Class	14	1			14
Presentations / Seminar	1	10	1		11
Midterms	1	20	1		21
Final	1	25	1		26
Total Workload					114