ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | ECZ406 | ||||
| Course Name: | Pharmaceutical Toxicology | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Prof. Dr. SEMRA ŞARDAŞ | ||||
| Course Lecturer(s): | PROF. DR. SEMRA ŞARDAŞ | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | It aims to contribute to general information about the harmful effects of chemical substances, to enlighten their mechanism of action and to evaluate the possible risks on humans based on experimental studies on biological test systems, and to convey the importance and applications of rational drug use, safety monitoring. |
| Course Content: | Obtain technical knowledge, application and preparation skills about Systemic Toxicology, Environmental and Occupational Toxicology, Pharmacovigilance and its applications, Addiction Toxicology (Substance Addiction and Drug Abuse), First Aid and Antidote Mechanisms in Poisonings, Pesticides, Herbal Poisonings and treatment, Animal Poisonings and treatment. |
Learning Outcomes
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The students who have succeeded in this course;
1) Evaluates the toxic effects of drugs 2) Identifies and evaluates drug-drug / nutrient interactions 3) Evaluates the toxic results of non-pharmaceutical xenobiotics 4) Applies the principles of rational and safe drug use in special patient groups 5) Risk assessment determines harmlessness limits 6) Identifies and evaluates the side / adverse effects of drugs. Knows pharmacovigilance practices. 7) Knows treatment methods in Animal and Plant Poisoning. 8) Evaluates the toxic results of non-pharmaceutical xenobiotics 9) Knows first aid and treatment methods in poisonings |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Systemic Toxicology I | |
| 2) | Systemic Toxicology II | |
| 3) | Environmental and Occupational Toxicology I | |
| 4) | Environmental and Occupational Toxicology II | |
| 5) | Pharmacovigilance and Practices I | |
| 6) | Pharmacovigilance and Practices II | |
| 7) | Addiction Toxicology (Substance Addiction and Drug Abuse) | |
| 8) | Spring Semester Midterm Period | |
| 9) | First Aid and Antidote Mechanisms in Poisoning I | |
| 10) | First Aid and Antidote Mechanisms in Poisoning II | |
| 11) | Pesticides I | |
| 12) | Pesticides II | |
| 13) | Herbal Poisoning and Treatment | |
| 14) | Animal Poisoning and Treatment | |
| 15) | Spring Semester Final Exam Period |
Sources
| Course Notes / Textbooks: | “Casarett & Doull's Toxicology: The basic science of poisons Klaassen CD, Amdur MO,Doull J; (3rd Ed, 1986) Macmillan Publishing |
| References: | Principles of Toxicology: Environmental and Industrial Applications, 3rd Edition,2015 Stephen M. Roberts, Robert C. James, Phillip L. Williams (Editors) Occupational Toxicology Edited By Chris Winder, Neill H. Stacey 2019 by CRC Pres |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | ||||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 2 | 2 | 2 | 2 | 2 | 2 | 2 | ||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | ||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | ||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 2 | 2 | 2 | 2 | 2 | 2 | 2 | ||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | ||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | ||||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | ||||
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 3 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 2 |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 3 |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 2 |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 42 |
| Study Hours Out of Class | 14 | 85 |
| Midterms | 1 | 2 |
| Final | 1 | 2 |
| Total Workload | 131 | |