ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | ECZ404 | ||||
| Course Name: | Pharmacotherapy | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Prof. Dr. MEHMET FERİT İSBİR | ||||
| Course Lecturer(s): | Prof. Dr. Mehmet F. İsbir | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | The aim of this course is to give information about principles of pharmacoterapy, rational drug use, dermatologic disorders, OTC, drugs used in emesis-vomitting, diarrhea-constipation, endocrine system disorders, nutritional disorders, gynecologic and obstetric disorders, renal disorders, urologic disorders, respiratory disorders, antitussive agents and drug monitoring |
| Course Content: | Principles of Pharmacoterapy rational drug use Stages of life parenteral nutrition OTC Dermatologic disorders and treatment Emesis-Vomiting Diarrhea Constipation Nutrional disorders and treatment Obesity Gynecologic and obstetric disorders and treatment Contraception Pregnancy and lactation Urologic disorders and treatment (erectile dysfunction) Respiratory diseases (Asthma-COPD) and treatment Antitussive Agents Renal diseases and treatment Endocrine diseases and drug therapy Therapeutic drug monitoring |
Learning Outcomes
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The students who have succeeded in this course;
1) The students will learn at the end of this course • General principles of pharmacotherapy, , rational drug use, stages of life, parenteral nutrition 2) At the end of this course, the students will learn and understand OTC 3) will have the understanding of drugs used in emesis-vomitting and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and druginteractions 4) will have the understanding of drugs used in diarrhea-constipation and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and druginteractions 5) will have the understanding of drugs used in asthma and COPD and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and druginteractions 6) will have understanding about therapeutic drug monitoring 7) will have the understanding of drug used in endocrine system disorders and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions 8) Dermatologic disorders and treatment ,will have the understanding of drugs used for Dermatologic disorders disorders and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and druginteractions 9) At the end of this course, the students will learn and understand nutrional disorders, obesity and treatment. 10) gynecologic and obstetric disorders and treatment will have the understanding of drugs used for Gynecologic and obstetric disorders and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions 11) At the end of this course, the students will learn and understand drug use in pregnancy and lactation. 12) Renal disorders and treatment , will have the understanding of drugs used for Urologic disorders and can define and give examples of mchanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions 13) Urologic disorders and treatment , will have the understanding of drugs used for Urologic disorders and can define and give examples of mchanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Principles of Pharmacoterapy rational drug use | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 2) | Stages of life parenteral nutrition OTC | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 3) | Emesis-Vomiting | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 4) | Constipation-diarrhea | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 5) | Respiratory diseases (Asthma-COPD) and treatment | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 6) | Antitussive Agents | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 7) | Drug monitoring (mid-term) | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 8) | Endocrine diseases and treatment | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 9) | Dermatologic disorders and treatment | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 10) | Nutrional disorders Obesity and treatment | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 11) | Gynecologic and obstetric disorders and treatment Contraception | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 12) | Pregnancy and lactation | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 13) | Renal diseases and treatment | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
| 14) | Urologic disorders and treatment (erectile dysfunction) | Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
Sources
| Course Notes / Textbooks: | Brunton L.L., Hılal-Dandan,R.,( 2017). Erdem Ş.R. (çev ed.)Goodman & Gilman’ın Farmakoloji ve Tedavi El kitabı, McGraw Hill Education, Güneş Tıp Kitabevleri Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education |
| References: | Brunton L.L., Hılal-Dandan,R.,( 2017). Erdem Ş.R. (çev ed.)Goodman & Gilman’ın Farmakoloji ve Tedavi El kitabı, McGraw Hill Education, Güneş Tıp Kitabevleri Brunton L.L., Hılal-Dandan,R.,Knollmann,B.C. Goodman and Gilman’s The pharmacological Basis of therapeutics,McGraw Hill Education Wells, B.G., Schwinghammer, T.L., DiPiro,J.T., DiPiro, C.V. (2017) Pharmacotherapy Handbook, McGraw Hill Education |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
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3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
12 |
13 |
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| Program Outcomes | |||||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |||||||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |||||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |||||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |||||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |||||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |||||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 2 |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 28 |
| Study Hours Out of Class | 14 | 42 |
| Midterms | 1 | 2 |
| Final | 1 | 2 |
| Total Workload | 74 | |