ISTINYE UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code: | ECZ403 | ||||
| Course Name: | Pharmacology 3 | ||||
| Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Compulsory Courses | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Prof. Dr. MEHMET FERİT İSBİR | ||||
| Course Lecturer(s): | Prof. Dr. Mehmet F. İsbir | ||||
| Course Assistants: |
Course Objective and Content
| Course Objectives: | The aim of this course is to give information about in drugs used in neoplastic disorders and infections, vitamins and hormones, bone and joint disorders, drug development and regulation, vaccines and treatment pharmacology of respiratory system and antitussive drugs, antianemic drugs and their mechanism of actions, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions, drug treatment in special patient populations |
| Course Content: | Cancer and drugs used in neoplastic disorders Antiviral agents Antifungal drugs Antiamoebic and Antiprotozoal drugs Antimalarial drugs Anthelmintic drugs Drugs used in ectoparasitic infection Antianemics Vitamins and deficiency Hormones Bone and joint disorders and treatment Drug treatments in special patient population Drug development and regulation Vaccines |
Learning Outcomes
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The students who have succeeded in this course;
1) At the end of this course, the students will learn and understand chemotherapeutics and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and druginteractions 2) Antivirals •will have the understanding of antivirals and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions 3) At the end of this course, the students will learn and understand antifungal drugs can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects and drug interactions 4) At the end of this course, the students will learn and understand antiamobic, antiprotosal and antimalarial drugs, their effects and mechanisms of action, indications and side effects, give examples. 5) At the end of this course, the students will learn and understand anthelmintic drugs, the effects of drugs used against ectoparasites and their mechanisms of action, indications, side effects, and give examples. 6) Antianemics will have the understanding of antianemics and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions 7) At the end of this course, the students will learn and understand vitamins and its place in the treatment of their deficiency-related diseases. 8) Hormones • will have the understanding of hormones; deficiency 9) Bone and joint disorders and treatment, will have the understanding of drugs used for Bone and joint disorders and can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and druginteractions 10) At the end of this couerse the students will have the understanding of drug treatment in special patient population 11) At the end of this course the students will have the understanding of drug development and regulation, vaccines |
Course Flow Plan
| Week | Subject | Related Preparation |
| 1) | Cancer and drugs used in neoplastic disorders | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 2) | Antiviral agents | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 3) | Antifungal drugs | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 4) | Antiamoebic and Antiprotozoal drugs Antimalarial drugs | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 5) | Anthelmintic drugs | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 6) | Review | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 7) | Drugs used in ectoparasitic infection (Midterm Exam) | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 8) | Antianemics | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 9) | Vitamins and deficiency | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 10) | Hormones | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 11) | Bone and joint disorders and treatment | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 12) | Drug treatments in special patient population | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 13) | Drug development and regulation Vaccines | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
| 14) | General review | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
Sources
| Course Notes / Textbooks: | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2007) Netter’in Resimli Farmakolojisi, Mehmet İsbir (çeviren) Nobel Tıp Kitabevleri Whalen, K., Feild, C.(yard.ed.), Radhakrishnan R.(yard.ed.) (2020) Lippincott Görsel Anlatımlı Çalışma Kitapları, Ulugöl, A. Karadağ, Ç.H., Dökmeci, D. (çeviri ed.) Nobel Tıp kitabevleri Katzung,B.G., Masters,S.B.,Trevor,A.J. (2016) Temel ve Klinik Farmakoloji, Akkan G ve ark (çev ed.) Nobel Tıp Kitabevleri Kayaalp O.S. (ed) (2018). Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Pelikan Yayıncılık |
| References: | Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2007) Netter’in Resimli Farmakolojisi, Mehmet İsbir (çeviren) Nobel Tıp Kitabevleri Whalen, K., Feild, C.(yard.ed.), Radhakrishnan R.(yard.ed.) (2020) Lippincott Görsel Anlatımlı Çalışma Kitapları, Ulugöl, A. Karadağ, Ç.H., Dökmeci, D. (çeviri ed.) Nobel Tıp kitabevleri Katzung,B.G., Masters,S.B.,Trevor,A.J. (2016) Temel ve Klinik Farmakoloji, Akkan G ve ark (çev ed.) Nobel Tıp Kitabevleri Kayaalp O.S. (ed) (2018). Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Pelikan Yayıncılık Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders. Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange. |
Course - Program Learning Outcome Relationship
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
6 |
7 |
8 |
9 |
10 |
11 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 |
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |||||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 |
Course - Learning Outcome Relationship
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 3 |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 3 |
Assessment & Grading
| Semester Requirements | Number of Activities | Level of Contribution |
| Midterms | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
Workload and ECTS Credit Calculation
| Activities | Number of Activities | Workload |
| Course Hours | 14 | 56 |
| Study Hours Out of Class | 14 | 40 |
| Midterms | 1 | 2 |
| Final | 1 | 2 |
| Total Workload | 100 | |