Pharmacy
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code: ECZ303
Course Name: Pharmacology 1
Semester: Fall
Course Credits:
ECTS
4
Language of instruction: Turkish
Course Condition:
Does the Course Require Work Experience?: No
Type of course: Compulsory Courses
Course Level:
Bachelor TR-NQF-HE:6. Master`s Degree QF-EHEA:First Cycle EQF-LLL:6. Master`s Degree
Mode of Delivery: Face to face
Course Coordinator: Prof. Dr. MEHMET FERİT İSBİR
Course Lecturer(s): Prof. Dr. Mehmet F. İsbir
Course Assistants:

Course Objective and Content

Course Objectives: This course provide a comprehensive understanding of the principles of pharmacology and the effects and mechanism of action of drugs on various organ systems.
The aim of this course is to give information about Basic Principles of pharmacology, the routes of drug administration, mechanism of drug interactions,pharmacodynamics, pharmacokinetics, drugs used to affect the autonomic nervous systems, drugs used in disorders of the central nervous system.
Course Content: General Principles of Pharmacology
General Principles of Pharmacokinetics , the routes of drug administration
General Principles of Pharmacokinetics, ADME
Mechanism of drug interaction,
General Principles of Pharmacodynamics and Receptors
General principles of autonomic pharmacology
Drugs used to affect the autonomic nervous system-Adrenergic Drugs Sympathomimetics
Antiadrenergic Drugs
Sympatholytics
Parasympathomimetic and parasympatholytic drugs
General principles of central nervous system pharmacology and drugs used to affect the central nervous system
Sedative-Hypnotic Drugs
Anxiolytic Drugs
Antidepressants
Antipsychotic Agents
Antiepileptic Agents

Learning Outcomes

The students who have succeeded in this course;
1) Students understand and explain the basic principles of pharmacology including ADME process, receptor-drug relationship, basic principles of drug action and interaction. The students will learn at the end of this course • Basic Principles of pharmacology and will be able to define the general terms/principles of pharmacology • General principles of the routes of drug administration, mechanism of drug interaction, factors influencing drug effects, and will be able to define / to give examples of mechanism of drug interaction.
2) The students will learn at the end of this course ; General principles of pharmacokinetics, ADME
3) The students will learn at the end of this course General principles of pharmacodynamics, receptors and signalling, receptor subtypes, signal transduction, second-messenger pathways etc., general mechanism of drug actions. •will be able to define/will have the understanding of pharmacodynamics/pharmacokinetics
4) • Introduction to physiology/pathophysiology of autonomic ans somatic nervous system and drugs used to affect the autonomic and somatic nervous system, general principles of autonomic pharmacology • Introduction to physiology/pathophysiology of central nervous system and drugs used to affect the central nervous system, general principles of central nervous system pharmacology • will have the understanding of drugs used to affect the autonomic and somatic nervous system • will have the understanding of drugs used to affect the central nervous system •can define and give examples of mechanism of action, their pharmacodynamics/pharmacokinetics, advers effects, and drug interactions

Course Flow Plan

Week Subject Related Preparation
1) General Principles of Pharmacology
2) General Principles of Pharmacokinetics, ADME, the routes of drug administration
3) General Principles of Pharmacokinetics
4) Mechanism of drug interaction,
5) General Principles of Pharmacodynamics and Receptors
6) General principles of autonomic pharmacology Drugs used to affect the autonomic nervous system
7) Sympathomimetics- (Midterm Exam)
8) Sympatholytics
9) Parasympathomimetic and parasympatholytic drugs
10) General principles of central nervous system pharmacology and drugs used to affect the central nervous system
11) Sedative-Hypnotic Drugs Anxiolytic Drugs
12) Antidepressants
13) Antipsychotic Agents
14) Antiepileptic Agents

Sources

Course Notes / Textbooks: Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2007) Netter’in Resimli Farmakolojisi, Mehmet İsbir (çeviren) Nobel Tıp Kitabevleri
Whalen, K., Feild, C.(yard.ed.), Radhakrishnan R.(yard.ed.) (2020) Lippincott Görsel Anlatımlı Çalışma Kitapları, Ulugöl, A. Karadağ, Ç.H., Dökmeci, D. (çeviri ed.) Nobel Tıp kitabevleri
Katzung,B.G., Masters,S.B.,Trevor,A.J. (2016) Temel ve Klinik Farmakoloji, Akkan G ve ark (çev ed.) Nobel Tıp Kitabevleri
Kayaalp O.S. (ed) (2018). Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Pelikan Yayıncılık.
References: Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2007) Netter’in Resimli Farmakolojisi, Mehmet İsbir (çeviren) Nobel Tıp Kitabevleri
Whalen, K., Feild, C.(yard.ed.), Radhakrishnan R.(yard.ed.) (2020) Lippincott Görsel Anlatımlı Çalışma Kitapları, Ulugöl, A. Karadağ, Ç.H., Dökmeci, D. (çeviri ed.) Nobel Tıp kitabevleri
Katzung,B.G., Masters,S.B.,Trevor,A.J. (2016) Temel ve Klinik Farmakoloji, Akkan G ve ark (çev ed.) Nobel Tıp Kitabevleri
Kayaalp O.S. (ed) (2018). Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Pelikan Yayıncılık
Raffa R.B., Rawls, S.M., Portyansky Beyzarov, E. (2014) Netter’s Illustrated Pharmacology, Elsevier Saunders.
Whalen, K., Finkel,R.(coll.ed.), Panavelil T.A..(coll.ed.) Harvey R.A. (series ed) (2015) Lippincott Illustrated Reviews (6th ed), Wolters Kluwer
Katzung,B.G.,(2018) Basic and Clinical Pharmacology (14th ed.), McGraw-Hill Education, Lange.
GOODMAN AND GİLMAN'S THE PHARMACOLOGİCAL BASİS OF THERAPEUTİCS, TWELFTH EDİTİON 12TH EDİTİON BY LAURENCE BRUNTON (AUTHOR), BRUCE CHABNER (AUTHOR), BJORN KNOLLMAN (AUTHOR) ISBN-13: 978-0071624428

Course - Program Learning Outcome Relationship

Course Learning Outcomes

1

2

3

4
Program Outcomes
1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. 2 2 2 2
2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently.
3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. 1 1 1
4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods.
5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes.
6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. 3 3 3 3
7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates.
8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products.
9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. 3 3 3 3
10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. 3 3 3 3
11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. 3 3 3 3

Course - Learning Outcome Relationship

No Effect 1 Lowest 2 Average 3 Highest
       
Program Outcomes Level of Contribution
1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. 2
2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently.
3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. 1
4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods.
5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes.
6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. 3
7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates.
8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products.
9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. 3
10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. 3
11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. 3

Assessment & Grading

Semester Requirements Number of Activities Level of Contribution
Midterms 1 % 30
Final 1 % 70
total % 100
PERCENTAGE OF SEMESTER WORK % 30
PERCENTAGE OF FINAL WORK % 70
total % 100

Workload and ECTS Credit Calculation

Activities Number of Activities Workload
Course Hours 14 56
Study Hours Out of Class 14 40
Midterms 1 2
Final 1 2
Total Workload 100