Molecular Biology and Genetics (English) | |||||
Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 |
Course Code: | MBG211 | ||||
Course Name: | Biophysics | ||||
Semester: | Fall | ||||
Course Credits: |
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Language of instruction: | English | ||||
Course Condition: | |||||
Does the Course Require Work Experience?: | No | ||||
Type of course: | Compulsory Courses | ||||
Course Level: |
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Mode of Delivery: | Face to face | ||||
Course Coordinator: | Araş. Gör. KAAN ADACAN | ||||
Course Lecturer(s): | Assist. Prof. Esma Nur Okatan, Assist. Prof. Denizhan Karış | ||||
Course Assistants: |
Course Objectives: | The aim of the course is to teach the students the basic principles of physics and the basic principles of physics to apply them to biological systems. |
Course Content: | This course will focus on the measurement, physical quantitites, unit systems; bonds and biophysical features of water and its role in organisims; forces, weight; compression, stress, strain and shearing forces; biomechanics, biomechanical features of bones, movement system, biomechanics of muscles and joints,; work energy and metabolism; energy flow in organisms, bioenergitics and thermodynamics laws; sturcture of membrane, transport mechanisms through membranes, diffusion, osmosis; electrical properties of cells, voltage gated ion channels, electrical and bioelectric potentials, Hodgkin & Huxley models; neuronal tranmission in myelin sheated nerve fibers, basic principles for ECG, EEG and EMG; aminoacids, peptides, proteins, radiation; fluid mechanics, Bernouilli and Poiseuille princibles, viscosity, dynamics in circulaiton, pump systems in organism, biophysics of blood circulation; surface tension, dynamics in respiration, biophysics of respiration; mirrors, lenses and image, biophysics of vision; sounds, auditory response, hearing, basic princibles in ultrasound; clinical applications of biophysical princibles. |
The students who have succeeded in this course;
1) Acquires general principles of physics and the behavior of the material when it is exposed to physical effects (force, heat, electric field and magnetic field). 2) Learns the importance of the laws of physics in understanding biological phenomena 3) Analyzes and applies basic biomechanical concepts, analysis of movement and other activities, motion control, vectors, rotational moment, gravity, center of gravity, balance, leverage systems and biomechanical properties of body region and extremities. 4) Discusses the principles of circulatory system, respiratory system and sesnse of sight and hearing, and neuronal transmission 5) Has knowledge about the mechanisms of molecular and physical interactions in the formation of diseases. |
Week | Subject | Related Preparation |
1) | Definition, history and methodology of biophysics | |
2) | Intermolecular interactions, Biophysical properties of the water | |
3) | Bioenergetic and unit systems | |
4) | Invention, classification and function of the ion channels, electrochemical driving force,Nernst equation potential, Patch Calmp technique | |
5) | Structure of Membrane; Transport Mechanisms Through Membranes; Fick Laws, Goldman-Hodgkin-Katz Equation, Membrane potential modulation | |
6) | Detailed discussion about membrane potential | |
7) | Generation and characteristics of action potentials, In a simulated neuron the response of the action potentials to altering parameters | |
8) | General Review | |
9) | Characteristics and recording of compound action potentials. Neuronal Transmission in Myelin Sheated Nerve Fibers; Basic Principles of ECG, EEG and EMG | |
10) | Biophysics of muscle contraction, signal conduction, reading EMG and ECG traces, heat production in the muscle, Hill equations | |
11) | Nervous System | |
12) | Biophysics of Sensation | |
13) | Radiation Biophysics | |
14) | General Review |
Course Notes / Textbooks: | Biophysics Demystified, Daniel Goldfarb, 3Mc Graw Hill Publications, 2011; Physics for Scientists and and Engineers, Raymond A. Serway and John W. Jewett, 6th Edition, Thomson Brooks/Cole, 2004. |
References: | Yoktur |
Course Learning Outcomes | 1 |
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Program Outcomes | ||||||||||||
1) Has a theoretical and practical background in biology, chemistry, physics and mathematics, which constitute the basic knowledge in the field of molecular biology and genetics. | 3 | 3 | 2 | 3 | 2 | |||||||
2) Can explain biological phenomena and events at molecular level and relate them to other basic sciences and engineering applications. | ||||||||||||
3) Has the basic laboratory knowledge and skills required by the field. | ||||||||||||
4) Works in accordance with scientific principles and ethical rules. | ||||||||||||
5) Uses procedural and mathematical software programs required for the analysis and basic evaluation of biological data at least at the European Computer License Basic Level. | ||||||||||||
6) Has the knowledge, culture and skills to follow the literature and current methods related to his field. | ||||||||||||
7) Will be able to identify the main problem in line with the needs in health, agriculture, animal husbandry, environment, industry and similar issues and offer the necessary solutions by using up-to-date technology. | ||||||||||||
8) Has the knowledge and ability to evaluate biological phenomena and events at the level of systems from an evolutionary point of view. | ||||||||||||
9) Has the ability to be involved in individual and group work, to prepare and carry out projects on specific topics, and to make written and oral presentations. | ||||||||||||
10) Uses at least one foreign language in reading, writing and speaking at B1 General Level in terms of European Language Portfolio criteria. | ||||||||||||
11) Has the ability to identify social and global problems using his / her field knowledge and to be a part of the solution in interdisciplinary cooperation. | ||||||||||||
12) Respects social, cultural and individual differences, universal values and human rights in his / her scientific and professional activities. |
No Effect | 1 Lowest | 2 Average | 3 Highest |
Program Outcomes | Level of Contribution | |
1) | Has a theoretical and practical background in biology, chemistry, physics and mathematics, which constitute the basic knowledge in the field of molecular biology and genetics. | 3 |
2) | Can explain biological phenomena and events at molecular level and relate them to other basic sciences and engineering applications. | |
3) | Has the basic laboratory knowledge and skills required by the field. | |
4) | Works in accordance with scientific principles and ethical rules. | |
5) | Uses procedural and mathematical software programs required for the analysis and basic evaluation of biological data at least at the European Computer License Basic Level. | |
6) | Has the knowledge, culture and skills to follow the literature and current methods related to his field. | |
7) | Will be able to identify the main problem in line with the needs in health, agriculture, animal husbandry, environment, industry and similar issues and offer the necessary solutions by using up-to-date technology. | |
8) | Has the knowledge and ability to evaluate biological phenomena and events at the level of systems from an evolutionary point of view. | |
9) | Has the ability to be involved in individual and group work, to prepare and carry out projects on specific topics, and to make written and oral presentations. | |
10) | Uses at least one foreign language in reading, writing and speaking at B1 General Level in terms of European Language Portfolio criteria. | |
11) | Has the ability to identify social and global problems using his / her field knowledge and to be a part of the solution in interdisciplinary cooperation. | |
12) | Respects social, cultural and individual differences, universal values and human rights in his / her scientific and professional activities. |
Semester Requirements | Number of Activities | Level of Contribution |
Midterms | 1 | % 40 |
Final | 1 | % 60 |
total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 40 | |
PERCENTAGE OF FINAL WORK | % 60 | |
total | % 100 |
Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
Course Hours | 13 | 0 | 3 | 39 | |||
Study Hours Out of Class | 13 | 0 | 5 | 65 | |||
Midterms | 1 | 0 | 20 | 20 | |||
Final | 1 | 0 | 30 | 30 | |||
Total Workload | 154 |