| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code: | UNI347 | ||||
| Course Name: | The Relationship between Metabolic Paths and Health in the Organism | ||||
| Semester: | Spring | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | Yes | ||||
| Type of course: | University Elective | ||||
| Course Level: |
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| Mode of Delivery: | E-Learning | ||||
| Course Coordinator: | Prof. Dr. HİKMET KOÇAK | ||||
| Course Lecturer(s): | Prof. Dr. Hikmet Koçak | ||||
| Course Assistants: |
| Course Objectives: | In this courses where the chemical reactions occurring in living organisms are studied; the metabolic events in which the biomolecules like proteins, carbohydrates and lipids take place and their interactions with each other will be explained to the students. It is also aimed to gain the competencies related to metabolism, to establish some relationships with biochemistry in the professional field and to gain the ability to evaluate them as a whole. |
| Course Content: | It is the functioning of the main metabolic pathways of the organism in a healthy state and raising awareness about pathological conditions in daily life. |
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The students who have succeeded in this course;
1) Must be able to distinguish the structural differences of biochemical macromolecules. 2) Must be able to list the concept of nutritional energy sources and the body’s energy stores. 3) Must be able to explain the energy metabolism of carbohydrates, lipids, protein. 4) Must define postprandial status and explain hormonal changes in postprandial status. 5) Must be able to explain the digestion, absorption and outcome of food. 6) Must be able to explain the conversion pathways of glucose in the liver and its metabolism in other tissues. 7) Must be able to explain the outcome of lipoproteins and amino acids in postprandial status. 8) Must be able to define fasting and explain the metabolic changes in short-term fasting. 9) Must be able to explain the role of liver and adipose tissue in short term fasting. 10) Must be able to explain the occurring metabolic changes and roles of liver and adipose tissue in prolonged fasting. 11) Must be able to explain the basal metabolism (resting metabolic rate), physical activity, and control of body weight. 12) Must be able to explain the importance of carbohydrates, essential fatty acids, essential amino acids, vitamins and minerals which suply the basic nutritional requirements. |
| Week | Subject | Related Preparation |
| 1) | Basic Concepts and Explanation of The Syllabus | Lecture Notes-presentations notes |
| 2) | Structural Overview of Basic Elements of Metabolic Pathways in the Organism | Lecture Notes-presentations notes |
| 3) | Events Affecting the Energy Requirement of the Body | Lecture Notes-presentations notes |
| 4) | Proteins- definition, properties, structure, types and Metabolism | Lecture Notes-presentations notes |
| 5) | Lipid Metabolism | Lecture Notes-presentations notes |
| 6) | The Carbohydrates and Metabolism | Lecture Notes-presentations notes |
| 7) | Integration of Metabolism (fasting/starving-fed state, postprandial Status) | Lecture Notes-presentations notes |
| 8) | Ramadan Feast (Holiday) | |
| 9) | Student Presentations | |
| 10) | Student Presentations | |
| 11) | Student Presentations | |
| 12) | Student Presentations | |
| 13) | Student Presentations | |
| 14) | Student Presentations |
| Course Notes / Textbooks: | Ders Notları-sunumlar Lecture Notes-presentations notes |
| References: | 1. Tıbbi Biyokimya, Gürdöl F., Nobel Tıp Kitabevleri, İstanbul, 2019 2. Harper'ın Biyokimyası, Nobel Tıp Kitabevleri, İstanbul, 2016 3. Lippincott Görsel Anlatımlı çalışma Kitapları Biyokimya, Harvey RA, Ferrier DR. (Çeviri editörü: Ulukaya E.): 5. baskı, Nobel Tıp Kitabevleri, 2014 4. Marks’ Tıbbi Biyokimyanın Esasları Klinik yaklaşım, Lieberman M, Peet A. (Çeviri editörleri: Amanvermez R, Avcı B.): 2nd edition, İstanbul Tıp Kitabevleri, 2017 |
| Course Learning Outcomes | 1 |
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| Program Outcomes | ||||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | ||||||||||||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | ||||||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | ||||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | ||||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | ||||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | ||||||||||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | ||||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | ||||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | ||||||||||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | ||||||||||||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | ||||||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. |
| Semester Requirements | Number of Activities | Level of Contribution |
| Attendance | 1 | % 10 |
| Homework Assignments | 1 | % 45 |
| Presentation | 1 | % 45 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 100 | |
| PERCENTAGE OF FINAL WORK | % | |
| total | % 100 | |
| Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
| Course Hours | 2 | 0 | 14 | 16 | 60 | ||
| Study Hours Out of Class | 1 | 4 | 4 | 10 | 18 | ||
| Presentations / Seminar | 1 | 4 | 4 | 10 | 18 | ||
| Homework Assignments | 1 | 5 | 4 | 10 | 19 | ||
| Total Workload | 115 | ||||||