| Pharmacy | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code: | ECZ059 | ||||
| Course Name: | Advanced Biochemistry | ||||
| Semester: |
Spring Fall |
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| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | Yes | ||||
| Type of course: | Departmental Elective | ||||
| Course Level: |
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| Mode of Delivery: | E-Learning | ||||
| Course Coordinator: | Dr. Öğr. Üy. ELİF YAVUZ DOKGÖZ | ||||
| Course Lecturer(s): | Dr. Öğretim Üyesi Elif YAVUZ DOKGÖZ | ||||
| Course Assistants: |
| Course Objectives: | The 'Advanced Biochemistry' course is suitable for students who have completed the Basic Biochemistry education. The content of the course will include up-to-date techniques that biochemistry and basic sciences benefit from. Within the scope of the course, biochemical pathways in specific diseases will be covered through databases. In particular, biochemical pathways and energy metabolism will be explained by making use of existing literature evidence in relation to diseases. |
| Course Content: | Within the scope of the course, biochemical pathways in specific diseases will be covered through databases. In particular, biochemical pathways and existing literature evidence related to diseases will be used. Intracellular energy metabolism in disease and well-being will be explained. |
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The students who have succeeded in this course;
1) Comprehends the importance of clinical biochemical data for diagnosis, screening and treatment of various diseases. 2) Understands the importance of biochemical data in the light of current literature for the diagnosis and treatment of various diseases 3) Becomes aware of the changing energy metabolisms in illness and well-being. 4) Knows the important cancer pathways in Cancer Biochemistry. |
| Week | Subject | Related Preparation |
| 1) | Metabolism Overview | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 2) | Altered Energy Metabolisms Specific to Cancer | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 3) | Using Metabolic Pathway Maps | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 4) | With Which Methods Can Cell Energy Metabolism Be Measured? | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 5) | Cancer Pathways I HIF-1α Signaling Pathway | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 6) | Cancer Pathways II P53 Signal Pathway | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 7) | Cancer Pathways III PI3K-Akt Signaling Pathway | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 8) | Midterm | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 9) | Cancer Pathways IV ECM-Receptor Interactions | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 11) | Cancer Pathways VI JAK-STAT Signaling Pathway | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 12) | Cancer Pathways VII MAPK Signaling Pathway | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 13) | Cancer Pathways VIII Pentose Phosphate Pathway | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| 15) | Final Exam | Human-Physiology-Biochemistry-and-Basic-Medicine. LAURENCE A. COLE; PETER R. KRAMER. 2016 Elsevier Inc. |
| Course Notes / Textbooks: | Lippincott Biyokimya. Görsel Anlatımlı Çalışma Kitapları. Yayınevi: Nobel Tıp Kitabevi |
| References: | Lippincott Illustrated Reviews Biochemistry. Yayınevi: Lippincott Williams & Wilkins. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics |
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
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| Program Outcomes | |||||||||||
| 1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | |||||||||||
| 2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |||||||||||
| 3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | |||||||||||
| 4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |||||||||||
| 5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |||||||||||
| 6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | |||||||||||
| 7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |||||||||||
| 8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |||||||||||
| 9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |||||||||||
| 10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | |||||||||||
| 11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | |||||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | |
| 2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | |
| 3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 2 |
| 4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | |
| 5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | |
| 6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | |
| 7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | |
| 8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | |
| 9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | |
| 10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | |
| 11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. |
| Semester Requirements | Number of Activities | Level of Contribution |
| Application | 1 | % 30 |
| Final | 1 | % 70 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 30 | |
| PERCENTAGE OF FINAL WORK | % 70 | |
| total | % 100 | |
| Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
| Course Hours | 14 | 3 | 1 | 1 | 70 | ||
| Midterms | 1 | 3 | 1 | 1 | 5 | ||
| Final | 1 | 3 | 1 | 1 | 5 | ||
| Total Workload | 80 | ||||||