Pharmacy | |||||
Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 |
Course Code: | ECZ058 | ||||
Course Name: | Food Toxicology | ||||
Semester: | Fall | ||||
Course Credits: |
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Language of instruction: | Turkish | ||||
Course Condition: | |||||
Does the Course Require Work Experience?: | No | ||||
Type of course: | Departmental Elective | ||||
Course Level: |
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Mode of Delivery: | E-Learning | ||||
Course Coordinator: | Dr. Öğr. Üy. SİNEM HELVACIOĞLU AKYÜZ | ||||
Course Lecturer(s): | Dr. Öğr. Üyesi Sinem Helvacıoğlu Akyüz | ||||
Course Assistants: |
Course Objectives: | The main purpose of this course is the formation and sources of toxic compounds in foods; To inform students about chemical structures, to teach the negative effects of toxic components on health, to provide information on methods and safety limits to control hazards. |
Course Content: | This course includes the Definition of toxic food components and factors affecting toxicity, Criteria, methods and tests used in the toxicological evaluation of foods, Food allergies and hypersensitivity, Toxic compounds naturally found in foods, Toxicological evaluation of pesticides and veterinary drugs, Foodborne microbial and parasitic poisonings and diseases, Food additives and their toxicological evaluation, Evaluation of food packaging materials in terms of food safety, Toxicological evaluation of heavy metals and other environmental contaminants, Irradiation of foods and toxicological evaluations, radioactive contaminants, Food processing methods and toxicological evaluation of the compounds formed, Toxicological evaluation of newly developed foodstuffs and genetic modification applications in foods, National and international regulations in toxicological evaluations, National and international regulations on toxicological evaluations. |
The students who have succeeded in this course;
1) Students who successfully complete this course will have knowledge and skills about various purpose additives and their toxicity. 2) Students who successfully complete this course will have knowledge and skills about toxic residues in nutrients. 3) Students who successfully complete this course will have knowledge and skills about toxic impurities in nutrients. 4) Students who successfully complete this course will be able to know the toxicological evaluation of pesticides, veterinary drugs and food additives. 5) Students will know bacteria, mold toxins and animal toxins. 6) Students will have information about the toxicological evaluation of food additives. |
Week | Subject | Related Preparation |
1) | Introduction and Food additives | |
2) | General Classification of Additives | |
3) | Chemicals in Foods I | |
4) | Chemicals in Foods II | |
5) | Natural contaminants I | |
6) | Natural contaminants II | |
7) | Environmental pollutants, Metals I | |
8) | Spring Term Midterm Exam Period | |
9) | Environmental pollutants, Metals II | |
10) | Environmental Pollutants, Detergents and packaging materials | |
11) | International Cooperation in Food Safety | |
12) | Environmental Pollutants, Acrylamide/PAH | |
13) | Pesticide Residues | |
14) | Carcinogenicity of food contaminants | |
15) | Spring Final Exam Period |
Course Notes / Textbooks: | Lecture Notes. Toksikoloji Ders Kitabı. (1988). Prof. Dr. Zeliha İmre. İstanbul: İstanbul Üniversitesi, Eczacılık Fakültesi. Toksikoloji. (2005). Prof. Dr. Nevin Vural. Ankara: Ankara Üniversitesi, Eczacılık Fakültesi Yayınları No: 73. Toksikoloji. (2001). Prof. Dr. İsmet Dökmeci. İstanbul: Nobel Tıp Kitabevleri. Casarett and Doull's Toxicology. (2001). Klaassen, C.D. Unites States of America: McGraw-Hill Companies. Goldfranks Toxicologic Emergencies. (2002). Flomenbaum, N.E., Howland, M.A., Goldfrank, L.R., Lewin, N.A., Hoffman, R.S., Nelson, L.S. Unites States of America: McGraw-Hill Companies. Clinical Management of Poisoning and Drug Overdose. (1998). Haddad, L.M., Shannon, M.W., Winchester, J.F. Unites States of America: W.B. Saunders Company. Principles and Methods of Toxicology. (2008). Hayes, A.W. Unites States of America: Informa Healthcare. Medical Toxicology. (1988). Ellenhorn, M.J., Barceloux D.G. Netherlands: Elsevier Science Publisher. Pesticide, Veterinary and Other Residues in Food. (2004). Watson, D.H. Boca Raton: CRC Press. Pesticide Residues and Drinking Water: Human Exposure and Risks. (2004). Hamilton, D., Crossley, S. England: John Wiley and Sons. |
References: | FDA- web site: https://www.fda.gov/ T.C. Tarım ve Orman Bakanlığı sitesi: https://www.tarimorman.gov.tr/ EFSA-web site: https://www.efsa.europa.eu/en/topics/topic/food-enzymes JECFA-web site: https://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/en/ |
Course Learning Outcomes | 1 |
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Program Outcomes | |||||||||||
1) Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 | 2 | 2 | 2 | 2 | 2 | |||||
2) Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 3 | 3 | 3 | 3 | 3 | 3 | |||||
3) Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 3 | 3 | 3 | 3 | 3 | 3 | |||||
4) Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 1 | 1 | 1 | 1 | 1 | 1 | |||||
5) Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 1 | 1 | 1 | 1 | 1 | 1 | |||||
6) Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 2 | 2 | 2 | 2 | 2 | 2 | |||||
7) Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 1 | 1 | 1 | 1 | 1 | 1 | |||||
8) He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 1 | 1 | 1 | 1 | 1 | 1 | |||||
9) Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 | 3 | 3 | 3 | 3 | 3 | |||||
10) As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 2 | 2 | 2 | 2 | 2 | 2 | |||||
11) He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 2 | 2 | 2 | 2 | 2 | 2 |
No Effect | 1 Lowest | 2 Average | 3 Highest |
Program Outcomes | Level of Contribution | |
1) | Applies and develops the universal and social dimensional effects of basic, professional and technological knowledge in the field of pharmacy as well as pharmacy practice interdisciplinary by following legal, deontological and ethical rules. | 2 |
2) | Defines the terminology related to the pharmacy profession; solves problems , accesses scientific information in the field of pharmacy, after monitoring and evaluating the current literature, applies , communicates, shares by using information technologies effectively and efficiently. | 3 |
3) | Uses theoretical and practical knowledge about the anatomical structure of the human body, the physiological working principles of systems, biochemical, immunological events in the organism and microorganisms. | 2 |
4) | Uses basic and advanced analytical techniques and methods by running qualitative/quantitative analyzes and interprets the findings by using appropriate statistical methods. | 1 |
5) | Defines medicinal plants, herbal drugs and active substances; gains the skills for the development of natural products used for medical purposes. | 1 |
6) | Applies patient-centered and individualized pharmaceutical care service together with other healthcare personnel within the framework of rational drug use by using the principles of clinical pharmacy, pharmacoeconomics, pharmacotherapy and phytotherapy. | 1 |
7) | Knows the biological properties, structure-activity relationships, and metabolisms of drugs and gains the skill for the synthesize and development of new drug candidates. | 2 |
8) | He/She is competent at formulations, production, stability, quality assurance, licensing, patent studies, legal regulations of products containing natural origin and / or synthetic active substances, advanced therapy medicinal products, radiopharmaceuticals and cosmetic products. | 2 |
9) | Interprets the pharmacokinetic and pharmacodynamic properties of drugs, the factors that change their effect, their toxic effects, pharmacolygical activities and their risk assessment method. Reports the drug interactions and adverse drug reactions, monitors and applies the theoretical/practical knowledge for preventing them. | 3 |
10) | As a health professional in his/her profession he/she acts as a caregiver, decision maker, communicator, manager, lifelong learner, instructor, leader and researcher, he/she complies with the principles of evidence-based pharmacy by making teamwork for the benefit of society, national and universal values. | 3 |
11) | He/She works in various fields such as community pharmacy, hospitals, pharmaceutical medical devices, herbal products and cosmetics sectors, health institutions and agencies, clinical research organizations , universities and R&D centers. | 2 |
Semester Requirements | Number of Activities | Level of Contribution |
Midterms | 1 | % 30 |
Final | 1 | % 70 |
total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 30 | |
PERCENTAGE OF FINAL WORK | % 70 | |
total | % 100 |
Activities | Number of Activities | Workload |
Course Hours | 13 | 26 |
Study Hours Out of Class | 15 | 55 |
Midterms | 1 | 2 |
Final | 1 | 2 |
Total Workload | 85 |