| Medical Biology and Genetics (DR) | |||||
| PhD | TR-NQF-HE: Level 8 | QF-EHEA: Third Cycle | EQF-LLL: Level 8 | ||
| Course Code: | TGY6010 | ||||
| Course Name: | Regulation of Gene Expression | ||||
| Semester: | Fall | ||||
| Course Credits: |
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| Language of instruction: | Turkish | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | Departmental Elective | ||||
| Course Level: |
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| Mode of Delivery: | Face to face | ||||
| Course Coordinator: | Prof. Dr. VEYSEL SABRİ HANÇER | ||||
| Course Lecturer(s): | Prof. Dr. Veysel Sabri Hançer | ||||
| Course Assistants: |
| Course Objectives: | Examining the factors and mechanisms that operate in controlling gene expression at different organizational levels |
| Course Content: | Examination of differentiation and gene expression in organisms at different organizational levels |
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The students who have succeeded in this course;
1) Based on doctoral qualifications, to develop and deepen current and advanced knowledge in the field with original thought and/or research at the level of expertise and to reach original definitions that will bring innovation to science. 2) To comprehend various interdisciplinary interactions related to the field; Achieving original results by using knowledge that requires expertise in analyzing, synthesizing and evaluating new and complex ideas. 3) To be able to systematically approach new information in the field and to gain high-level skills in research methods related to the field. 4) To contribute to science by presenting an original, publishable study that brings innovation to science, develops a new scientific method, or applies a known method to a field. 5) To expand the boundaries of knowledge in the field by publishing a scientific article related to the field in national and/or international refereed journals. 6) To be able to develop new ideas and methods related to the field by using high-level mental processes such as creative and critical thinking, problem solving and decision making. 7) Ability to communicate effectively, demonstrating competence in defending original views within a community of experts. 8) Being able to communicate and discuss at an advanced level in written, oral and visual language in at least one foreign language. 9) To contribute to the process of becoming an information society by introducing technological, social and cultural advances in the academic and professional context. 10) Ability to establish functional interaction using strategic decision-making processes in problem solving. 11) To be able to produce solutions to social, scientific and ethical issues encountered in the field and business life and to support the development of these values. 12) To observe social, scientific and ethical values during the collection, interpretation and announcement of data related to the field, and to be able to teach and supervise these values. |
| Week | Subject | Related Preparation |
| 1) | Genome structure | |
| 2) | Genome structure, identification of gene expression | |
| 3) | Relationship between cell differentiation and regulation of gene expression | |
| 4) | Transcriptional control mechanisms | |
| 5) | Molecular mechanisms operating in the formation of different cell types | |
| 6) | Transcriptional control | |
| 7) | Post-transcriptional control | |
| 8) | Regulation of gene expression in the prokaryotic system | |
| 9) | Regulation of gene expression in the eukaryotic system | |
| 10) | Eukaryotic mechanisms 1 | |
| 11) | Eukaryotic mechanisms 2 | |
| 12) | Epigenetic factors in the regulation of gene expression 1 | |
| 13) | Epigenetic factors in the regulation of gene expression 2 | |
| 14) | Non-coding regulatory RNAs |
| Course Notes / Textbooks: | Molecular Biology of the Gene (Ed: Watson Baker, Bell Gann, Lewine Losick) Molecular Biology (Ed: David P. Clark) Genes IX (Ed: Benjamin Lewin) Genomes. 2nd edition. Brown TA. Oxford: Wiley-Liss; 2002. Güncel yayınlar, web siteleri, güncel kitaplar |
| References: | Molecular Biology of the Gene (Ed: Watson Baker, Bell Gann, Lewine Losick) Molecular Biology (Ed: David P. Clark) Genes IX (Ed: Benjamin Lewin) Genomes. 2nd edition. Brown TA. Oxford: Wiley-Liss; 2002. Güncel yayınlar, web siteleri, güncel kitaplar |
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| Program Outcomes | ||||||||||||
| 1) Follows the current literature in the field of Medical Biology and Genetics, collects information, analyzes and synthesizes it with appropriate evaluation methods and guides clinical practices. | ||||||||||||
| 2) Uses appropriate methods and technological structures for scientific research, establishes the appropriate hypothesis, and determines research methods. | ||||||||||||
| 3) Interprets the results obtained as a result of scientific research, transfers and develops the evidence-based knowledge obtained into applications, presents its results at national and international scientific meetings and publishes them in peer-reviewed journals. | ||||||||||||
| 4) Realizes the principles of lifelong learning by observing professional autonomy within the ethical, deontological and legal framework in Medical Biology and Genetics applications and scientific studies. | ||||||||||||
| 5) Provides interdisciplinary collaboration in academic and clinical environments and has knowledge and skills in problem solving and management. | ||||||||||||
| 6) Uses the information obtained from scientific research and literature for the benefit of society and ensures the shaping of health policies necessary to improve public health and takes part in these policies. | ||||||||||||
| 7) Trains biologists who combine clinical experience and academic knowledge, produce, plan and implement creative solutions in the field of medical biology and have qualified knowledge and skills. | ||||||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Follows the current literature in the field of Medical Biology and Genetics, collects information, analyzes and synthesizes it with appropriate evaluation methods and guides clinical practices. | 2 |
| 2) | Uses appropriate methods and technological structures for scientific research, establishes the appropriate hypothesis, and determines research methods. | |
| 3) | Interprets the results obtained as a result of scientific research, transfers and develops the evidence-based knowledge obtained into applications, presents its results at national and international scientific meetings and publishes them in peer-reviewed journals. | |
| 4) | Realizes the principles of lifelong learning by observing professional autonomy within the ethical, deontological and legal framework in Medical Biology and Genetics applications and scientific studies. | |
| 5) | Provides interdisciplinary collaboration in academic and clinical environments and has knowledge and skills in problem solving and management. | |
| 6) | Uses the information obtained from scientific research and literature for the benefit of society and ensures the shaping of health policies necessary to improve public health and takes part in these policies. | |
| 7) | Trains biologists who combine clinical experience and academic knowledge, produce, plan and implement creative solutions in the field of medical biology and have qualified knowledge and skills. | 1 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Homework Assignments | 1 | % 10 |
| Presentation | 1 | % 10 |
| Midterms | 1 | % 20 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
| Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
| Course Hours | 14 | 0 | 3 | 42 | |||
| Study Hours Out of Class | 14 | 0 | 8 | 112 | |||
| Presentations / Seminar | 1 | 5 | 3 | 8 | |||
| Homework Assignments | 1 | 5 | 3 | 8 | |||
| Midterms | 1 | 10 | 3 | 13 | |||
| Final | 1 | 10 | 3 | 13 | |||
| Total Workload | 196 | ||||||