| Physiotherapy and Rehabilitation (English) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code: | UNI320 | ||||
| Course Name: | Health & Microbiome | ||||
| Semester: | Fall | ||||
| Course Credits: |
|
||||
| Language of instruction: | English | ||||
| Course Condition: | |||||
| Does the Course Require Work Experience?: | No | ||||
| Type of course: | University Elective | ||||
| Course Level: |
|
||||
| Mode of Delivery: | E-Learning | ||||
| Course Coordinator: | Dr. Öğr. Üy. DENİZ SERTEL ŞELALE | ||||
| Course Lecturer(s): | İbrahim Çağatay Acuner, Pınar Yurdakul Mesutoğlu, Deniz Sertel Şelale, Ayhan Mehmetoğlu | ||||
| Course Assistants: |
| Course Objectives: | The aim of this course is to convey information on; - fundamentals of human microbiota & microbiome - formation and development of microbiota - factors that affect the composition of microbiota - effects of microbiota on human health - association of microbiota with diseases - pharmaceutical modulation of microbiota |
| Course Content: | This course includes theoretical lectures regarding human microbiota and it’s effects on human health and association with diseases. |
|
The students who have succeeded in this course;
1) Should be able to define microbiota, microbiome and metagenome concepts. 2) Should be able to describe human microbiota and explain how its formed. 3) Should be able to explain the factors that affect the composition of microbiota. 4) Should be able to define the effects of microbiota on human health. 5) Should be able to explain the association of microbiota with diseases. 6) Should be able to discuss the use of pharmaceutical preparations that modulate microbiota in promotion of health. |
| Week | Subject | Related Preparation |
| 1) | Introduction to microbiota, microbiome and metagenome concepts | Review of the course materials |
| 2) | Transmission and development of microbiota | Review of the course materials |
| 3) | Nutritional modulation of the gut microbiome | Review of the course materials |
| 4) | Microbiota perturbations: Dysbiosis and Disease | Review of the course materials |
| 5) | Microbiota & Obesity; Type-2 Diabetes and Cancer | Review of the course materials |
| 6) | Gut microbiome and host immunity | Review of the course materials |
| 7) | Microbiota & Gut-Brain / Gut-Lung Axis | Review of the course materials |
| 8) | Mid term exam | Review of the course materials |
| 9) | Consumption of antibiotics and microbiota | Review of the course materials |
| 10) | Fecal transplantation | Review of the course materials |
| 11) | Nutritional modulation of the gut microbiome for metabolic health and healthy longevity | Review of the course materials |
| 12) | Prebiotics, probiotics and next generation pharmaceutical modulation of the gut microbiome | Review of the course materials |
| 13) | One health approach, and microbiota | Review of the course materials |
| 14) | Multi omics approach and future trends | Review of the course materials |
| 15) | Final Exam | Review of the course materials |
| Course Notes / Textbooks: | Tungland B. Human Microbiota in Health and Disease. Academic Press;2018. ISBN 9780128146491 |
| References: | • Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012 Oct;13(10):701-12. doi: 10.1038/nrn3346. Epub 2012 Sep 12. PMID: 22968153. • Sonnenburg JL, Bäckhed F. Diet-microbiota interactions as moderators of human metabolism. Nature. 2016 Jul 7;535(7610):56-64. doi: 10.1038/nature18846. PMID: 27383980; PMCID: PMC5991619. • Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015 Apr-Jun;28(2):203-209. PMID: 25830558; PMCID: PMC4367209. • Kim S, Covington A, Pamer EG. The intestinal microbiota: Antibiotics, colonization resistance, and enteric pathogens. Immunol Rev. 2017 Sep;279(1):90-105. doi: 10.1111/imr.12563. PMID: 28856737; PMCID: PMC6026851. • Sonnenburg JL, Sonnenburg ED. Vulnerability of the industrialized microbiota. Science. 2019 Oct 25;366(6464):eaaw9255. doi: 10.1126/science.aaw9255. PMID: 31649168. • Mikroorganizmalar ve insan vücudu ile olan etkileşimleri Microorganisms and their interaction with human body. Rıdvan Çetin et al. DOI: 10.5455/pmb.1-1422383762 • Tang ZZ, Chen G, Hong Q, Huang S, Smith HM, Shah RD, Scholz M, Ferguson JF. Multi-Omic Analysis of the Microbiome and Metabolome in Healthy Subjects Reveals Microbiome-Dependent Relationships Between Diet and Metabolites. Front Genet. 2019 May 17;10:454. doi: 10.3389/fgene.2019.00454. PMID: 31164901; PMCID: PMC6534069. • İntestinal mikrobiyota ve obezite ilişkisi, The relationship between intestinal microbiota and obesity. Tuba tekin et al. Derleme 2018; 27: 95-99. • Ichim TE, Patel AN, Shafer KA. Experimental support for the effects of a probiotic/digestive enzyme supplement on serum cholesterol concentrations and the intestinal microbiome. J Transl Med. 2016 Jun 22;14(1):184. doi: 10.1186/s12967-016-0945-2. PMID: 27333764; PMCID: PMC4918082. • Kuugbee ED, Shang X, Gamallat Y, Bamba D, Awadasseid A, Suliman MA, Zang S, Ma Y, Chiwala G, Xin Y, Shang D. Structural Change in Microbiota by a Probiotic Cocktail Enhances the Gut Barrier and Reduces Cancer via TLR2 Signaling in a Rat Model of Colon Cancer. Dig Dis Sci. 2016 Oct;61(10):2908-2920. doi: 10.1007/s10620-016-4238-7. Epub 2016 Jul 6. PMID: 27384052. • Salvucci E. The human-microbiome superorganism and its modulation to restore health. Int J Food Sci Nutr. 2019 Nov;70(7):781-795. doi: 10.1080/09637486.2019.1580682. Epub 2019 Mar 7. PMID: 30843443. |
| Course Learning Outcomes | 1 |
2 |
3 |
4 |
5 |
6 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Program Outcomes | |||||||||||||||
| 1) Physiotherapy defines the basic medical sciences concepts and principles related to physiotherapy and rehabilitation evaluation processes, basic elements and methodological application principles. | |||||||||||||||
| 2) He/She lists clinical evaluation tools and methods by analyzing the collected information about evaluation in physiotherapy according to reasoning and problem solving processes. | |||||||||||||||
| 3) Explain the indications, contraindications, side effects and intervention strategies of the physiotherapy approaches and the mechanisms used to cope with functional disability and possible intervention methods. Sorts the near and far term targets according to functional levels. | |||||||||||||||
| 4) It is based on the physiotherapy information related to the general health of the service area. It defines the health and lifestyle profile, deficiencies, body structure and function, activity-participation level of the person and determines the evaluation and treatment priorities in this direction. | |||||||||||||||
| 5) With the data obtained from physiotherapy assessments, it creates and implements an individual-oriented physiotherapy intervention plan in accordance with the diagnosis of physiotherapy by using information literacy, evidence-based clinical decision-making processes. | |||||||||||||||
| 6) It applies to the service area the exercise program planned as well as consultancy in the protection and development of health outside the disease states. | |||||||||||||||
| 7) Develops a scientific research proposal about physiotherapy and rehabilitation. | |||||||||||||||
| 8) He leads the clinical practice in accordance with the quality standards in the process of establishment and management of the institutions / organizations / centers providing physiotherapy and rehabilitation services. | |||||||||||||||
| 9) As a physical therapist, he works with his colleagues and professionals from different disciplines. | |||||||||||||||
| 10) Evaluates information sources with a critical approach by adapting to new conditions, learning new ideas, developing new ideas, and giving importance to quality. | |||||||||||||||
| 11) By using professional information sources and physiotherapy techniques effectively, it reaches information, adopts positive attitude and behavior model and determines learning objectives. | |||||||||||||||
| 12) Uses effective communication skills by respecting the confidentiality of service areas from a biopsychosocial point of view during physiotherapy evaluation and interventions. | |||||||||||||||
| 13) It adopts the ethical, deontological and legal framework for the collection, recording and reporting of necessary data during the physiotherapy evaluation and interventions. | |||||||||||||||
| 14) Observes the rights and responsibilities of the physicians in physiotherapy and rehabilitation practices and acts in accordance with the legislation and professional ethics rules in cooperation with the related disciplines. | |||||||||||||||
| 15) Physiotherapist takes responsibility with the understanding of interdisciplinary cooperation while preserving its identity, consciousness and professional autonomy. | |||||||||||||||
| No Effect | 1 Lowest | 2 Average | 3 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Physiotherapy defines the basic medical sciences concepts and principles related to physiotherapy and rehabilitation evaluation processes, basic elements and methodological application principles. | 2 |
| 2) | He/She lists clinical evaluation tools and methods by analyzing the collected information about evaluation in physiotherapy according to reasoning and problem solving processes. | 2 |
| 3) | Explain the indications, contraindications, side effects and intervention strategies of the physiotherapy approaches and the mechanisms used to cope with functional disability and possible intervention methods. Sorts the near and far term targets according to functional levels. | 2 |
| 4) | It is based on the physiotherapy information related to the general health of the service area. It defines the health and lifestyle profile, deficiencies, body structure and function, activity-participation level of the person and determines the evaluation and treatment priorities in this direction. | 2 |
| 5) | With the data obtained from physiotherapy assessments, it creates and implements an individual-oriented physiotherapy intervention plan in accordance with the diagnosis of physiotherapy by using information literacy, evidence-based clinical decision-making processes. | 1 |
| 6) | It applies to the service area the exercise program planned as well as consultancy in the protection and development of health outside the disease states. | 3 |
| 7) | Develops a scientific research proposal about physiotherapy and rehabilitation. | 1 |
| 8) | He leads the clinical practice in accordance with the quality standards in the process of establishment and management of the institutions / organizations / centers providing physiotherapy and rehabilitation services. | 1 |
| 9) | As a physical therapist, he works with his colleagues and professionals from different disciplines. | 2 |
| 10) | Evaluates information sources with a critical approach by adapting to new conditions, learning new ideas, developing new ideas, and giving importance to quality. | 1 |
| 11) | By using professional information sources and physiotherapy techniques effectively, it reaches information, adopts positive attitude and behavior model and determines learning objectives. | 2 |
| 12) | Uses effective communication skills by respecting the confidentiality of service areas from a biopsychosocial point of view during physiotherapy evaluation and interventions. | 2 |
| 13) | It adopts the ethical, deontological and legal framework for the collection, recording and reporting of necessary data during the physiotherapy evaluation and interventions. | 3 |
| 14) | Observes the rights and responsibilities of the physicians in physiotherapy and rehabilitation practices and acts in accordance with the legislation and professional ethics rules in cooperation with the related disciplines. | 2 |
| 15) | Physiotherapist takes responsibility with the understanding of interdisciplinary cooperation while preserving its identity, consciousness and professional autonomy. | 2 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Homework Assignments | 1 | % 20 |
| Midterms | 1 | % 20 |
| Final | 1 | % 60 |
| total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| total | % 100 | |
| Activities | Number of Activities | Preparation for the Activity | Spent for the Activity Itself | Completing the Activity Requirements | Workload | ||
| Course Hours | 14 | 0 | 3 | 42 | |||
| Homework Assignments | 1 | 20 | 1 | 21 | |||
| Midterms | 1 | 30 | 1 | 31 | |||
| Final | 1 | 30 | 1 | 31 | |||
| Total Workload | 125 | ||||||